Regulation of the Heat Shock Response in Bacteria

Schumann, Wolfgang

doi:10.1007/978-981-10-4651-3_2

Cited by 6 publications

(11 citation statements)

References 86 publications

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“…DNA topology influences transcription and thus, any change in the supercoiling pattern can result in a rapid and efficient alteration of the gene expression during stress conditions [18]. DNA topology has been shown to play an important role in pathogenicity of organisms such as Salmonella.…”

Section: Supercoilingmentioning

confidence: 99%

“…Temperature sensing can also occur by local DNA structures that affect the transcription of neighbouring genes. Particularly, intrinsically curved DNA regions characterized by AT-rich tracts are often located on the upstream of the promoter region and affect the binding ability of RNA polymerase due to temperature changes [18]. Bacterium Clostridium perfringens provides the best example as the promoter of the plc gene, which encodes for the enzyme phospholipase C. The promoter was found to have three A tracts which functioned as an RNA polymerase binding site [20,21].…”

Section: Promoter Curvaturementioning

confidence: 99%

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Microbial Mechanisms of Heat Sensing

2022

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Temperature is one of the ubiquitous signals that control both the development as well as virulence of various microbial species. Therefore their survival is dependent upon initiating appropriate response upon temperature fluctuations. In particular, pathogenic microbes exploit host-temperature sensing mechanisms for triggering the expression of virulence genes. Many studies have revealed that the biomolecules within a cell such as DNA, RNA, lipids and proteins help in sensing change in temperature, thereby acting as thermosensors. This review shall provide an insight into the different mechanisms of thermosensing and how they aid pathogenic microbes in host invasion.

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Section: Supercoilingmentioning

confidence: 99%

Section: Promoter Curvaturementioning

confidence: 99%

Microbial Mechanisms of Heat Sensing

2022

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“…Meanwhile, the exposure of heat shock to the cells in physiological saline solution supposedly stimulates the formation of those specific proteins. The unfolding of the proteins resulting from the sudden rise of temperature appears to be the primary signal that initialized the heat shock response (Schumann, 2017). The increase of temperature also promotes physiological changes that extensively enhance the ability of bacterial cells to endure such harmful environmental conditions (Shin, Kang, Kim & So, 2018), as indicated by high D T values.…”

Section: Data On Tablementioning

confidence: 99%

Heat Resistance of Candidate Probiotic Enterococcus faecalis R22B in Different Matrices

Lestari

Rinto

Wahyuni

et al. 2021

Squalen Bull. Marine Fisheries Postharvest Biotech.

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Fermented fish, including rusip and bekasam, contains lactic acid bacteria, some of which have probiotic properties. Considering the beneficial effect, the count of viable cells in probiotic carrier foods must be at least 10 6 CFU/g throughout the product shelf-life. The processing and storage condition significantly affect the viability of probiotics in carrier foods. This research was conducted to determine the heat resistance of probiotic candidate Enterococcus faecalis R22B isolated from rusip in three different media: bekasam, rusip, and physiological saline solution (NaCl 0.85%). E. faecalis R22B was heated in each medium at a temperature of 70 °C for 0, 2, 4, 8, and 12 min. The media characteristics showed differences within the parameters included pH values of 4.

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“…The GroE chaperonin system of E. coli , consisting of the 60 kDa GroEL and the 10 kDa GroES proteins assembled into ring complexes of 14 and seven sub-units, respectively, is encoded by the groE operon ( Tilly and Georgopoulos, 1982 ; Bukau and Horwich, 1998 ; Balchin et al, 2016 ). This operon is expressed principally from two promoters, one utilized in the presence of housekeeping sigma factor σ 70 , and the other, which is strongly induced due to the accumulation of unfolded proteins, in the presence of the alternative sigma factor, σ 32 (RpoH) ( Kusukawa and Yura, 1988 ; Lund, 2001 ; Kumar et al, 2015 ; Schumann, 2017 ). As σ 32 levels respond to unfolded protein, this provides a feedback loop to maintain proteostasis ( Kim et al, 2013 ).…”

Section: Introductionmentioning

confidence: 99%

Chaperonin Abundance Enhances Bacterial Fitness

Kumar

Chugh

Dutta

et al. 2021

Front. Mol. Biosci.

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The ability of chaperonins to buffer mutations that affect protein folding pathways suggests that their abundance should be evolutionarily advantageous. Here, we investigate the effect of chaperonin overproduction on cellular fitness in Escherichia coli. We demonstrate that chaperonin abundance confers 1) an ability to tolerate higher temperatures, 2) improved cellular fitness, and 3) enhanced folding of metabolic enzymes, which is expected to lead to enhanced energy harvesting potential.

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Regulation of the Heat Shock Response in Bacteria

Cited by 6 publications

References 86 publications

Microbial Mechanisms of Heat Sensing

Microbial Mechanisms of Heat Sensing

Heat Resistance of Candidate Probiotic Enterococcus faecalis R22B in Different Matrices

Chaperonin Abundance Enhances Bacterial Fitness

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