This study was conducted to examine the influence of female genital mutilation on women sexual activities in Oke-Ona community, Abeokuta North Local Government Area of Ogun-State, South-West Geopolitical Zone of Nigeria with respect to: sexual satisfaction, sexual desire and virginal penetration experience. In order to achieve its aim, the study raised three hypotheses, each on sexual satisfaction, sexual desire and virginal penetration experience. These hypotheses were tested through t-test statistical method via the Statistical Package for Social Sciences (SPSS) 23rd version. Results showed no positive interaction between genital mutilation and sexual satisfaction [t (109) = .560, P>.05]. It also revealed no significance in the mean difference frequency of sexual desire of genitally mutilated women compared to those not genitally mutilated [t (109) = - .640, P>.05]. Besides, the findings indicated no significant difference in the mean difference in the vaginal penetration experience between genitally mutilated women and those not genitally mutilated [t (109) = −1.523, P>.05]. Furtherance to the conclusions drawn, the implications of the findings were discussed and recommendations were made.