Rejuvenation of the Aging Lip With an Injectable Acellular Dermal Graft (Cymetra)

Sclafani, Anthony P.; Romo, Thomas; Jacono, Andrew A.

doi:10.1001/archfaci.4.4.252

Cited by 61 publications

(27 citation statements)

References 11 publications

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“…50,51 Cymetra (LifeCell, Branchburg, NJ) is another human-derived collagen containing micronized cadaveric-derived collagen. 52 The cosmetic effect lasts about 4 to 7 months, depending on the area of treatment, injection technique, and amount of injected collagen. 53 No skin test for hypersensitive reactions are required for any of these human-derived collagen products.…”

Section: Bovine Collagen Key Pointsmentioning

confidence: 99%

Adverse reactions to injectable soft tissue fillers

Requena

Christensen

et al. 2011

Journal of the American Academy of Dermatology

288

237

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Section: Bovine Collagen Key Pointsmentioning

confidence: 99%

Adverse reactions to injectable soft tissue fillers

Requena

Christensen

et al. 2011

Journal of the American Academy of Dermatology

288

237

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“…A randomized trial comparing Zyplast® (bovine collagen) and Cymetra® (human collagen) injections to the upper lip showed that Cymetra® had a much higher posttreatment value than Zyplast® by the 12-month visit, with bruising being the most commonly observed adverse effect for both fillers. [23] Because Cymetra® is of human origin, skin testing is not required prior to use.…”

Section: Human Collagenmentioning

confidence: 99%

Intradermal fillers for minimally invasive treatment of facial aging

Lin¹,

Shah²,

Dhinakar³

et al. 2016

PAR

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The ever-increasing interest in retaining a youthful physical appearance has facilitated the development of various minimally invasive dermatological techniques. The use of intradermal fillers can be incorporated into dermatological practices with minimal overhead costs. This strategy addresses facial volume loss and dynamic lines, which are the main features of facial aging. Moreover, intradermal fillers provide an array of flexible treatment options for a balanced and holistic result to dermatological practitioners. This paper reviews the different intradermal fillers categorized by biodegradable and non-permanent fillers including collagen based materials, hyaluronic acid and autologous fat, semi-permanent fillers including poly methyl methacrylate, poly-L-lactic acid and calcium hydroxyapatite microspheres, and permanent fillers including silicone. A discussion is provided of the commercial products made of these materials and their clinical efficacy in the treatment of facial aging. Key words:Intradermal fillers; facial aging; volumization; biodegradable and non-permanent fillers; semipermanent fillers; permanent fillers Xin Zhao is an associate professor at Xi'an Jiaotong University, China. Prior to starting this appointment, she was a postdoctoral fellow at Medical School and School of Engineering and Applied Sciences at Harvard University. Her research involves engineering the micro-and nanoscale systems for tissue regeneration and drug delivery.

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“…Also a longer lasting variant is available in the form of Cosmoplast is cross-linked with glutaraldehyde for greater stability. Cymetra (Life Cell Corp., Branchburg, NJ) is an intradermal injection product that is composed of cryofractured AlloDerm (Sclafani et al 2002a). Cymetra is provided as a freezedried powder with an average particle size of 123 µm and is reconstituted through the rehydration of 330 mg in 1 ml of 1% lidocaine hydrochloride.…”

Section: Human Collagenmentioning

confidence: 99%