Abstract:The research aims to find out whether there is any significant correlation between work motivation and self-efficacy and employee performance, mediated by job satisfaction in Regional Licensing and Investment Agency of East Kalimantan Province. The research method used in this research is a quantitative method. The data was collected using questionnaires and the sampling technique used in this research is saturated-sampling. Population and sample in this research is all employees working in Regional Licensing and Investment Agency of East Kalimantan Province with a total of 77 respondents. Data analysis method used in this research is Partial Least Square (PLS) method, using 3.0 SmartPLS program. The result of the research shows that motivation influences job satisfaction, selfefficacy influences job satisfaction, job satisfaction influences employee performance, selfefficacy influences employee performance, motivation influences employee performance mediated by job satisfaction, and self-efficacy influences employee performance mediated by job satisfaction.Keywords: motivation, self-efficacy, job satisfaction, employeeperformance.An organization has its vision, mission and objectives to be achieved, as a manifestation of the reasons why the organization is formed. Achieving the vision, mission and objectives of the organization requires optimal and maximum skill of all employees. Giving optimal, maximal, and effectivedirection to all employeeswill lead to optimal employee performance in reaching the vision, mission and objectives of the organization. Employees are a key figure in the success of an or-587 ganization. In order for an organization's activities to run properly, the organization must have broadminded employees with good skills and effort to manage the organization optimally, so that employee performance will increase.According to Setiawan and Waridin (2006), employee performance is the result or achievement of employees, which is assessed in terms of quality and quantity, based on the standards determined by the company. Good performance is optimal performance, which meets the standards set by the organization and supports the achievement of organizational goals as well. A good organization is an organization that seeks to improve the ability of its employees because it is a major factor to improve employee performance. Increase in employee performance will bring progress tothe organization to survive in the tight JAM 15, 4