Relation of Calorie Deficiency to Growth Failure in Children on Hemodialysis and the Growth Response to Calorie Supplementation

Somatomedin and Growth after Renal Transplantation

“…Some invetsigacors have attributed growth failure in chronic uremia to decreased caloric intake [33,381. Caloric intake of 70% or more of RDA [25] was considered to be compatible with resumption of growth [33].…”

“…Caloric intake of 70% or more of RDA [25] was considered to be compatible with resumption of growth [33]. Although the dietary intakes of our patients were not clearly defined before transplantation, after transplantation all patients in this series were on an unlimited diet providing at least 100% of RDA of caloric intake.…”

A Review: Short Stature in Renal Disease

“…Whereas dialysis alone fails to overcome the vitamin D-resistant osteodystrophy in renal failure, renal transplantation corrects this in most instances. This would explain the observations by Simmons and co-workers [10] that children grow after transplantation if adequate nutrition is provided. Growth also depends on the steroid regimen after transplantation.…”

“…The factor of malnutrition should not be overlooked, however, particularly in view of the data presented by Simmons and co-workers [10]. These authors studied growth rates of children who were on chronic dialysis and found that children who received more than 67% of the recommended daily caloric allowances grew much faster than children who had a lower caloric intake.…”

“…Factors contributing to short stature in children with renal disease have been investigated by several groups [1,2,10,13]. Acidosis and chronic malnutrition were believed to be among the most important causes of the growth failure.…”