Relationship between age and prostate size

Abstract

In a community-based study, the relationship between age and human prostate size was investigated in a population of men between the ages of 40 and 70 years to determine the normal prostate increase curve equation. One thousand male volunteers were randomly recruited from the Shanghai community, and the length, width, height, volume of the transition zone (TZ) and the whole prostates were measured by transrectal ultrasound (TRUS). Each volunteer was evaluated by the International Prostate Symptom Score (IPSS). Among those who completed the examination, the mean prostate parameters were all positively associated with increased age. There were statistically significant differences between each age group (P<0.05). The mean transition zone volume (TZV) had a higher increase rate with age than the mean total prostate volume (TPV), indicating that the enlargement of the TZ contributed the most to the increase in TPV. While all prostate parameters were positively correlated with the IPSS, the strongest correlation was associated with the TZ length (TZL) and TZV. The growth curve equations for prostate width, height and length were also positively associated with increasing age.

Real‐time registration of 3D to 2D ultrasound images for image‐guided prostate biopsy

“…Interestingly, reducing the 2D template image size used for registration to a 356 × 292 pixels AOI (64.08 × 52.56 mm 2 ) showed a decrease in TRE. This AOI is larger than an average healthy prostate length and height of approximately 40 × 30 mm 2 with a volume of 30 cm 3 ; however, many prostate glands with cancer are often enlarged and can fill this region with anatomical information. Since there is some variability when manually selecting fiducials, the chosen AOI would be influenced by an unknown bias in the TRE measurement given that the TRE was used for AOI selection.…”

Recommendation of fiducial marker implantation for better target tracking using MV imager in prostate radiotherapy

“…The inferior–superior direction is indicated by letter Z. In the X‐Y plane, the resolutions of the fiducial marker center locations were generated according to the resolution of grid template, which is 5 mm, while interval along the Z direction was determined by the size of the fiducial markers and the average‐sized prostate 12, 13. Total of 40 different fiducial marker implant patterns for four fiducial marker combinations were studied.…”

A study of prostate volumes in patients with spinal cord injury

“…PVs were compared to expected age-adjusted volumes of healthy men using the nomogram of Zackrisson et al 9 The values provided in this nomogram are similar to values presented in other available nomograms. [10][11][12] In patients who were older than 30 years during SCI, measured PVs were also compared to PVs adjusted to the age of injury. Continuous variables were compared using the ttest and categorical variables using Fischer's exact test and the chi square tests.…”