Relationship between chest CT scan findings with SOFA score, CRP, comorbidity, and mortality in ICU patients with COVID‐19

Abstract

Objective This study aimed to investigate the relationship between chest computed tomography (CT) scan findings with sequential organ failure assessment (SOFA) score, C‐reactive protein (CRP), comorbidity, and mortality in intensive care unit (ICU) patients with coronavirus disease 19 (COVID‐19). Method Adult patients (≥18 years old) with COVID‐19 who were consecutively admitted to the Imam‐Reza Hospital, Tabriz, East‐Azerbaijan Province, North‐West of Iran between March 2020 and August 2020 were screened and total of 168 patients were included. Demographic, clinical, and mortality data were gathered. Severity of disease was evaluated using the SOFA score system. CRP levels were measured and chest CT scans were performed. Results Most of patients had multifocal and bilateral ground glass opacity (GGO) pattern in chest CT scan. There were significant correlations between SOFA score on admission with multifocal and bilateral GGO ( P = .010 and P = .011, respectively). Significant relationships were observed between unilateral and bilateral GGO patterns with CRP ( P = .049 and P = .046, respectively). There was significant relationship between GGO patterns with comorbidities including overweight/obesity, heart failure, cardiovascular diseases, and malignancy ( P < .05). No significant relationships were observed between chest CT scan results with mortality ( P > .05). Conclusion Multifocal bilateral GGO was the most common pattern. Although chest CT scan characteristics were significantly related with SOFA score, CRP, and comorbidity in ICU patients with COVID‐19, a relationship with mortality was not significant.

COVID-19 Hastaları İçin Prognostik Faktörler ve Eozinofillerin Rolü

“…[12] However, the relationship between other symptoms and mortality could not be demonstrated both in the same study and in the study of Martos Pérez et al [14] There was a significant correlation between the extent of lung involvement and mortality. In the study of Hejazi et al [15] on intensive care patients in Iran, they found that multilobar involvement was associated with comorbidity and poor prognosis, but they could not associate it with mortality. However, the study of Aydemir et al [16] was similar to ours, they found a relationship between multilobar involvement and the severity and mortality of the disease.…”

Evaluación de tomografía computarizada y score SOFA pulmonar: relación de evaluación en pacientes con covid-19 y mortalidad en UCI

“…La literatura está dividida al reportar la efectividad de SOFA para el Covid-19. Algunos estudios demuestran una correlación significativa entre la TC y el SOFA al ingreso, afirmando que el SOFA es una buena herramienta para predecir la gravedad y el desenlace de la enfermedad (21) . Un SOFA mayor o igual a 2 en el momento del ingreso hospitalario puede ser un predictor de la necesidad de ingreso en la UCI (22) y un SOFA elevado en las primeras 48 horas puede sugerir una alta tasa de mortalidad (7) .…”