Relationship between computerized wheeze detection and lung function parameters in young infants

Fischer, Hendrik; Puder, Lia; Wilitzki, Silke; Usemann, Jakob; Bührer, Christoph; Godfrey, Simon; Schmalisch, Gerd

doi:10.1002/ppul.23310

Cited by 14 publications

(11 citation statements)

References 37 publications

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“…In this case, pendelluft swinging to the site of including the short-term monitoring of treatment effects in bronchiolitis, 49 and in the comparison of wheeze detection and lung function in infants. 50 A multi-sensor array system for "vibration response imaging"…”

Section: Measurementmentioning

confidence: 99%

“…In 2008, Pulmotrack (KarmelSonix, Haifa, Israel) was the first stand‐alone wheeze monitor to receive approval by the US Food and Drug Administration (FDA). It has been applied in several pediatric studies, including the short‐term monitoring of treatment effects in bronchiolitis, and in the comparison of wheeze detection and lung function in infants . A multi‐sensor array system for “vibration response imaging” (VRIxp, Deep Breeze, Or‐Akiva, Israel), that is, for the spatial mapping of chest sounds, was FDA approved in 2008 and has been used in a study of wheezes .…”

Section: Introductionmentioning

confidence: 99%

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The highs and lows of wheezing: A review of the most popular adventitious lung sound

Pasterkamp

2017

Pediatric Pulmonology

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Wheezing is the most widely reported adventitious lung sound in the English language. It is recognized by health professionals as well as by lay people, although often with a different meaning. Wheezing is an indicator of airway obstruction and therefore of interest particularly for the assessment of young children and in other situations where objective documentation of lung function is not generally available. This review summarizes our current understanding of mechanisms producing wheeze, its subjective perception and description, its objective measurement, and visualization, and its relevance in clinical practice.

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Section: Measurementmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The highs and lows of wheezing: A review of the most popular adventitious lung sound

Pasterkamp

2017

Pediatric Pulmonology

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“…In our sound spectrogram (time vs sound frequency), typical wheezing can be observed as a bright wave-type band from left to right, mainly in the high-pitched area of the expiratory phase. 34,35 After the assessment of the response to a methacholine inhalation challenge with an Astograph (Chest Co.), wheezing is not usually heard by auscultation, and a fine difference in the sound intensity and/or tone may be recognized by careful physicians.…”

Section: Discussionmentioning

confidence: 99%

Changes in the breath sound spectrum during methacholine inhalation in children with asthma

et al. 2017

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Background and objective: An effort-independent breath sound analysis is expected to be a safe and simple method for clinical assessment of changes in airway function. The effects of bronchoconstriction and bronchodilation on novel breath sound parameters in asthmatic children were investigated. Methods: The study population included 49 children with atopic asthma (male = 33; mean age: 10.2 years). We evaluated breath sound parameters of the highest frequency of the power spectrum (HFp), frequency limiting 50% and 99% of the power spectrum (F 50 and F 99 ) and roll-off from 600 Hz to the HFp (Slope). We also assessed new parameters obtained using the ratios of sound spectrum parameters (spectrum curve indices), such as the ratio of the third and fourth power area to the total power area (P 3 /P T and P 4 /P T ), the ratio of the third and fourth areas to the total area under the curve (A 3 /A T and B 4 /A T ) and the ratio of power and frequency at 75% of HFp and 50% of HFp (RPF 75 and RPF 50 ). This was measured before and after methacholine inhalation challenge and after β 2 agonist inhalation. Results: The parameters, F 50 and F 99 , showed no changes after methacholine inhalation. Conversely, the A 3 /A T (12.5-10.0%, P < 0.001), B 4 /A T (7.6-5.5%, P < 0.001), RPF 75 (6.7-4.0 dBm/Hz, P < 0.001) and RPF 50 (5.8-4.3 dBm/Hz, P < 0.001) were significantly decreased. These values returned to the original level after β 2 agonist inhalation. Conclusion: Spectrum curve indices indicate bronchoconstriction and bronchodilation. These parameters may play a role in the assessment of airway narrowing in asthmatic children.

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“…El uso de esta tecnología ha permitido una interpretación más objetiva de los ruidos respiratorios, pero también ha tenido oportunidades de tener un rol en la toma de decisiones clínicas respecto a la terapia de pacientes con enfermedades respiratorias. Varios estudios han mostrado que CORSA ha sido útil en pacientes con asma en la detección de sibilancias durante las pruebas de provocación bronquial, contando con una fuerte correlación con el grado de obstrucción bronquial que presenta el paciente 39,40 . En un estudio realizado en 22 lactantes con bronquiolitis aguda se pudo establecer la respuesta clínica al uso de salbutamol en relación al tipo de sibilancias que presentaba en el análisis acústico realizado 41 .…”

Section: Nuevos Avances En Auscultación Pulmonarunclassified

La auscultación pulmonar en el siglo 21

et al. 2020

Rev Chil Pediatr

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La auscultación pulmonar es parte fundamental del examen físico para el diagnóstico de las enfermedades respiratorias. La estandarización que ha alcanzado la nomenclatura de los ruidos respiratorios, sumado a los avances en el análisis computacional de los mismos, han permitido mejorar la utilidad de esta técnica. Sin embargo, el rendimiento de la auscultación pulmonar ha sido cuestionado por tener una concordancia variable entre profesionales de la salud. Aun cuando la incorporación de nuevas herramientas diagnósticas de imágenes y función pulmonar han revolucionado la precisión diagnóstica en enfermedades respiratorias, no existe tecnología que permita reemplazar la técnica de auscultación pulmonar para guiar el proceso diagnóstico. Por una parte, la auscultación pulmonar permite seleccionar a aquellos pacientes que se beneficiarán de una determinada técnica diagnóstica, se puede repetir cuantas veces sea necesario para tomar decisiones clínicas, y frecuentemente permite prescindir de exámenes adicionales que no siempre son fáciles de realizar o no se encuentran disponibles. En esta revisión se presenta el estado actual de la técnica de auscultación pulmonar y su rendimiento objetivo basado en la nomenclatura actual aceptada para los ruidos respiratorios, además de resumir la evidencia principal de estudios de concordancia de auscultación pediátrica y su análisis objetivo a través de nueva tecnología computacional.

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Relationship between computerized wheeze detection and lung function parameters in young infants

Abstract: CORSA can help identify neonates and young infants with subclinical airway obstruction and may prove useful in the follow-up of high-risk infants.

Cited by 14 publications

References 37 publications

The highs and lows of wheezing: A review of the most popular adventitious lung sound

The highs and lows of wheezing: A review of the most popular adventitious lung sound

Changes in the breath sound spectrum during methacholine inhalation in children with asthma

La auscultación pulmonar en el siglo 21

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