Relationship between patient-reported disease severity in osteoarthritis and self-reported pain, function and work productivity

Sadosky, Alesia; Bushmakin, Andrew G.; Cappelleri, Joseph C.; Lionberger, David R.

doi:10.1186/ar3121

Cited by 70 publications

(73 citation statements)

References 27 publications

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“…29,30 In our study, the prevalence of OA was higher in subjects with hypertension, cardiovascular disorders and diabetes. These comorbidities have also been reported by other authors, along with depression, dyslipidemia or other musculoskeletal conditions.…”

Section: Discussionsupporting

confidence: 43%

Assessing the magnitude of osteoarthritis disadvantage on people's lives: the MOVES study

Cunha-Miranda

Faustino

Alves³

et al. 2015

Revista Brasileira de Reumatologia (English Edition)

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r e v b r a s r e u m a t o l . 2 0 1 5;5 5(1):22-30 REVISTA BRASILEIRA DE REUMATOLOGIA w w w . r e u m a t o l o g i a . c o m . b r Quality of life Self-report a b s t r a c t Introduction: Osteoarthritis (OA) is one of the ten most disabling diseases in developed countries and one of the leading causes of pain and disability over the world. Early diagnosis increases the likelihood of preventing disease progression.Objectives: To estimate the prevalence of self-reported osteoarthritis and quality of life in Portuguese adults with 45 or more years old.Methods: Observational, cross-sectional study, implemented in households by face-to-face interview.Results: 1039 subjects with mean age of 62 years and 54.2% female were included. The prevalence of self-reported osteoarthritis was 9.9%. Knees and hands were the most frequent site of disease. The prevalence of OA was higher in women and in participants without professional activity. Presence of OA was higher in participants with comorbidities. Most subjects have done some treatment at some point in time for this disease: 94.5% had drug therapy, 49.5% physiotherapy, and 19.8% physical activity. Pain was associated with height, with some disease locations specifically neck, lower spine and shoulders, SF12 scores of quality of life, and measurements of impact in daily living, severity of disease and disability. The impact of OA in daily living was greater in subjects that had been on sick leave or stopped working due to OA, had worse physical and mental health, and with more severe of disease.Conclusion: This study confirmed that osteoarthritis is a very relevant disease with a high potential impact on quality of life, function and work ability and because of its prevalence with a very high growing social impact. r e v b r a s r e u m a t o l . 2 0 1 5;5 5(1):22-30 23 Avaliação da magnitude da desvantagem da osteoartrite na vida das pessoas: estudo MOVES Palavras-chave: Osteoartrite Qualidade de vida Auto-relato r e s u m o Introdução: A osteoartrite (OA) é uma das dez doenças mais incapacitantes nos países desenvolvidos e uma das principais causas de dor e incapacitação no mundo. O diagnóstico precoce aumenta a probabilidade de prevenção da progressão da doença. Objetivos: Estimar a prevalência de osteoartrite auto-referida e a qualidade de vida em adultos portugueses com 45 ou mais anos de idade. Métodos: Estudo observacional, transversal, implementado em domicílios por entrevista interpessoal. Resultados: Foram incluídos no estudo 1039 indivíduos com idade média de 62 anos, sendo 54,2% do gênero feminino. A prevalência de osteoartrite auto-referida foi de 9,9%. Os joelhos e as mãos foram o local mais freqüente da doença. A prevalência de OA foi maior em mulheres e em participantes sem atividade profissional. A presença de OA foi maior em participantes com comorbidades. A maioria dos indivíduos já tinham passado por algum tratamento em alguma ocasião de suas vidas para esta doença: 94,5% tiveram tratamento farmacológico, 49,5% fisioterapia, e 19,8% atividade física. ...

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Section: Discussionsupporting

confidence: 43%

Assessing the magnitude of osteoarthritis disadvantage on people's lives: the MOVES study

Cunha-Miranda

Faustino

Alves³

et al. 2015

Revista Brasileira de Reumatologia (English Edition)

View full text Add to dashboard Cite

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“…29,30 No nosso estudo, a prevalência de OA foi maior em indivíduos hipertensos, com transtornos cardiovasculares e diabetes. Essas comorbidades também foram relatadas por outros autores, juntamente com depressão, dislipidemia ou outros problemas musculosqueléticos.…”

Section: Discussionunclassified

“…4,13,30 Em nosso estudo, também observamos uma associação entre dor medida por EVA e impacto na vida diária, gravidade da doença e nível de incapacitação. Segundo a literatura, o alí-vio da dor é o principal motivador nos pacientes com OA, na busca de atenção médica.…”

Section: Discussionunclassified

“…É importante também compreender a relação entre OA, dor auto-referida e medidas de incapacitação, para que se tenha um conhecimento mais aprofundado com relação ao efeito que a OA exerce na vida do paciente, à progressão da doença, e aos caminhos para uma intervenção eficaz. 29,30 Para alguns autores, 22,30 dor e funcionamento são assumidos como resultados sintomáticos da OA que podem frequentemente ser considerados pelo paciente como parte da avaliação da eficácia farmacológica, em associação com suas percepç ões de gravidade e melhora. Em nosso estudo, os resultados apontam para uma relação entre o impacto no dia-a-dia do paciente, gravidade e incapacitação -que, no ponto de vista do paciente, são os desfechos que mais foram considerados como tendo associação com esta doença.…”

Section: Discussionunclassified

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Avaliação da magnitude da desvantagem da osteoartrite na vida das pessoas: estudo MOVES

Cunha-Miranda¹,

Faustino²,

Alves³

et al. 2015

Revista Brasileira de Reumatologia

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“…A patient's tendency to feel joint pain with increasing Osteoarthritis (OA) severity [1] has been reported and hip-joint pain is a factor that reduces Short Form 36 physical functioning [2] and walking speed [3]. Moreover, Mannoni et al [4] have reported that hip OA is strongly associated with disability, and Hall et al [5] have reported that hip OA causes decreased physical functioning on the Western Ontario and McMaster Universities Osteoarthritis Index.…”

Section: Introductionmentioning

confidence: 99%

Relationship between Hip Flexion Contracture and Hip-Joint Contact Force in Standing Posture: A Computer Simulation Study

Inai¹,

Edama²,

Takabayashi³

et al. 2017

J Ergonomics

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Mechanical stress on articular cartilage and long-duration standing postures are risk factors for hip osteoarthritis progression. This study aims to examine the relationship between hip flexion contracture and the hip-joint contact force in standing postures using computer simulation. A musculoskeletal model composed of seven segments (Head, Arms, and Trunk (HAT) and thighs, shanks, and two feet) was created. Various standing postures (708 variations) were generated, and five hip flexion contracture conditions were set: zero contracture and flexions of 0°, 10°, 20°, and 30°. A standing posture satisfying the hip flexion contracture condition with the minimum sum of the muscle activations was obtained as the optimal standing posture, and the hip-joint contact force in the optimal standing posture was calculated. A sensitivity analysis was conducted by varying four parameters (the objective function, physiological cross-sectional area, force-length relation, and muscle moment arm length). The hip-joint contact force and hip extensor muscle forces (i.e., those of the gluteus maximus, semitendinosus, semimembranosus, and biceps femoris long head) during standing increased with the development of hip flexion contracture. The hip-joint contact force for the standing posture with a 30° hip flexion contracture was almost twice that for the no-contracture condition (8.7 and 3.7 N/kg, respectively). The sensitivity analysis showed that variation of the four parameters did not affect our main finding. The main finding of this study is that hip-joint contact force during standing increases with the development of hip flexion contracture. The findings of this study may help to prevent hip osteoarthritis progression.

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Relationship between patient-reported disease severity in osteoarthritis and self-reported pain, function and work productivity

Cited by 70 publications

References 27 publications

Assessing the magnitude of osteoarthritis disadvantage on people's lives: the MOVES study

Assessing the magnitude of osteoarthritis disadvantage on people's lives: the MOVES study

Avaliação da magnitude da desvantagem da osteoartrite na vida das pessoas: estudo MOVES

Relationship between Hip Flexion Contracture and Hip-Joint Contact Force in Standing Posture: A Computer Simulation Study

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