Relationship of Riboflavin and Niacin with Cardiovascular Disease

Abstract

Cardiovascular disease is caused by different factors. These factors include innateness factors such as aging, biological factors such as high blood pressure, and environmental factors such as stress. This study examined the factors associated with cardiovascular disease and the ways to reduce its prevalence by analyzing the data within the Korean National Health and Nutrition Examination Reports from 2013 to 2017, and particularly the survey and examination data for people over 50 years old. The study population was divided into two groups: members of the first group consumed riboflavin and niacin at the recommended rate while those in the second group did not. Riboflavin intake was correlated with hypertension, hyperglycemia, and a low HDL-cholesterol level, whereas niacin intake was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level. The combination of niacin and riboflavin intakes was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level (P＜0.05). The combined intake of the recommended levels of riboflavin and niacin reduced the average physiological factor abnormality rate to 80%. Taken together, the beneficial effects of riboflavin and niacin can reduce the prevalence of cardiovascular disease.

Atherogenic Index of Plasma and Its Association with Risk Factors of Coronary Artery Disease and Nutrient Intake in Korean Adult Men: The 2013–2014 KNHANES

“…Calcium is notable as an antihypertensive agent, contributing to the inverse association between calcium and CVD risk [ 43 , 44 ]. Inadequate riboflavin intake was associated with increased hypertension and low HDL-C [ 45 ].…”

Asupan Dan Frekuensi Konsumsi Serat, Vitamin B3, dan Pufa Berhubungan dengan Profil Lipid dan Penyakit Jantung Koroner

“…Tidak adanya hubungan tersebut diketahui karena rerata asupan vitamin B3 responden cenderung sama serta asupannya rendah sehingga tidak mempunyai kontribusi untuk dapat mempengaruhi kadar lipid darah. Penelitian Ahn et al, (2019) pada responden usia >50 tahun di Korea menunjukkan asupan niasin sesuai kebutuhan (14−16 mg/hari) berhubungan signifikan dengan hipertensi, hiperglikemia, ukuran pinggang dan kadar kolesterol HDL rendah (p−value <0,05). Ketika niasin dikonsumsi sesuai dengan kebutuhan, tingkat prevalensi penyakit kardiovaskular berkurang 63% (OR=0,634, p−value <0,001) (Ahn et al, 2019).…”

“…Penelitian Ahn et al, (2019) pada responden usia >50 tahun di Korea menunjukkan asupan niasin sesuai kebutuhan (14−16 mg/hari) berhubungan signifikan dengan hipertensi, hiperglikemia, ukuran pinggang dan kadar kolesterol HDL rendah (p−value <0,05). Ketika niasin dikonsumsi sesuai dengan kebutuhan, tingkat prevalensi penyakit kardiovaskular berkurang 63% (OR=0,634, p−value <0,001) (Ahn et al, 2019).…”