Relative activity of psychotoxic drugs on the avian optic lobe

Experiences With Sacred Mushrooms and Psilocybin In Dialogue: Transdisciplinary Interpretations Of The “Velada”

“…As described in the section "The Honguito: the blood of Christ," or in Gudelia's testimony, these images involve sensory and somatic experiences. The presentation of these images could be explained by the activating effects of psilocybin on the visual, auditory, interoceptive, and somatosensory systems of the brain, as has been described in neuroscientific research with animal models since the 1960s and 1970s (Roberts and Barley 1967;Scholes and Gutnick 1970;Meldrum and Naquet 1971), and recently through functional magnetic resonance imaging in humans (Carhart-Harris et al 2012). However, the mere projection of images during the velada is not enough.…”

“…This was the great discovery that created new possibilities for scientific research during the second half of the twentieth century, particularly for the behavioral sciences, neurosciences, and for psychiatric medicine. Part of this research was conducted during the 1960s and 1970s using basic animal models with a comparative approach between the psychotomimetic or hallucinogenic substances, as they were known at the time, which included psilocybin with mescaline and lysergic acid diethylamide (LSD) (Kakolewski 1968;Roberts and Barley 1967;Scholes and Gutnick 1970). It was not until the 1990s, with the sophistication of psychophysical designs and the development of neuroimaging, that neuroscientific research was conducted on humans (Spitzer et al 1996;Vollenweider et al 1994).…”