Relative Bioavailability of Manganese Proteinate for Broilers Fed a Conventional Corn–Soybean Meal Diet

Wang, Funing; Lü, Lin; Li, Sufen; Liu, Songbai; Zhang, Liyang; Yao, Junhu; Luo, Xugang

doi:10.1007/s12011-011-9238-z

Cited by 27 publications

(17 citation statements)

References 15 publications

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“…Several previous studies showed that the activity and mRNA abundance of heart MnSOD linearly increased as dietary Mn levels increased when chicks fed diets supplemented with 60-180 mg of Mn/kg of diet for 21 days (Li et al, 2004(Li et al, , 2005Wang et al, 2012). Luo et al (2007) found that the heart MnSOD mRNA level was a more sensitive criterion for assessing the relative bioavailabilities of Mn sources than Mn accumulation in the tissues of broilers.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have shown that the bioavailabilities of organic Mn sources for broilers were closely related to their chelation strengths (Li et al, ; Luo et al, ; Wang et al, ). The organic Mn source with the moderate chelation strength displayed the highest relative bioavailability, followed by one with the strong chelation strength, and that with the weak chelation strength was as available as Mn sulphate.…”

Section: Discussionmentioning

confidence: 99%

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Relative bioavailability of humate–manganese complex for broilers fed a corn–soya bean meal diet

Zhao

Peng

et al. 2018

Animal Physiology Nutrition

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The experiment was conducted to investigate the bioavailability of manganese (Mn) from humate–Mn complex relative to Mn sulphate for the starter broilers fed a conventional corn–soya bean meal diet. A total of 560 1‐day‐old Arbor Acres male broiler chicks were randomly allotted to one of eight replicate cages (10 chicks per cage) for each of seven treatments in a completely randomized design involving a 2 × 3 factorial arrangement of treatments with two Mn sources (humate‐Mn and Mn sulphate) and three levels of added Mn (60, 120 or 180 mg Mn/kg) plus a Mn‐unsupplemented control diet containing 27.23 mg Mn/kg by analysis. At 14 days of age, the blood, liver, heart and tibia were collected for Mn analyses, and the activity and mRNA abundance of heart manganese superoxide dismutase (MnSOD). The results showed that humate‐Mn supplementation decreased feed intake from day 1 to day 14, whereas it did not influence (p > 0.20) body weight at day 14 as compared to Mn sulphate. The Mn source did not influence Mn concentration in the liver, heart and tibia, and the activity and mRNA abundance of heart MnSOD, while humate‐Mn decreased plasma Mn as compared to Mn sulphate. The Mn concentration in the plasma and heart, and the activity and mRNA abundance of heart MnSOD increased linearly as dietary Mn concentration increased. Based on slope ratios from multiple linear regressions of Mn concentrations in the plasma and heart, and the activity and mRNA abundance of heart MnSOD on daily intake amount of dietary analysed Mn, the bioavailability of humate–Mn complex relative to Mn sulphate (100%) was 82.8, 90.4, 82.8 and 81.9 respectively. These results indicated that the Mn from humate‐Mn complex was just as bioavailable as the Mn from Mn sulphate for the starter broilers (day 1–14).

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Relative bioavailability of humate–manganese complex for broilers fed a corn–soya bean meal diet

Zhao

Peng

et al. 2018

Animal Physiology Nutrition

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“…Chemical characteristics are considered important in predicting the bioavailabilities of chelated and complexed metals. A series of studies from our laboratory (Li et al, 2004(Li et al, , 2005Huang et al, 2009Huang et al, , 2013Wang et al, 2012;Liu et al, 2012a; has shown that the bioavailabilities of organic Mn, Zn, Cu, and Fe were closely related to their Q f values. Holwerda et al (1995) classified the organic trace mineral supplements with their Q f into 4 classes, in which the supplements with Q f values less than 10 have a weak chelation strength, those with Q f values between 10 and 100 have a moderate chelation strength, those with Q f values between 100 and 1,000 have a strong chelation strength, and those with Q f values greater than 1,000 have an extremely strong chelation strength.…”

Section: Discussionmentioning

confidence: 99%

“…The chemical characteristics of organic Fe sources may partially explain the discrepancies in their relative bioavailabilities. A series of studies from our laboratory (Li et al, 2004(Li et al, , 2005Huang et al, 2009Huang et al, , 2013Liu et al, 2012aLiu et al, , 2013Wang et al, 2012) have shown that the relative bioavailabilities of organic Mn, Zn, and Cu for broilers fed a conventional corn-soybean meal diet were closely related to their chelation strengths (quotient of formation [Q f ] values). The latest study from our laboratory demonstrated that iron proteinate with moderate chelation strength had a higher bioavailability than iron sulfate in enhancing hemoglobin (Hb) and total body Hb Fe of broilers fed a caseindextrose diet.…”

mentioning

confidence: 99%

“…The results from the present study indicated that under conventional diets supplemented with Fe levels at or near Fe requirement of broilers, using more sensitive gene expression indices of Fe-containing enzymes in target tissues, the multiple linear regression slope ratio method could more accurately estimate Fe bioavailabilties of Fe sources for broilers. Furthermore, in our laboratory, such similar methods have been successfully used for estimating Mn and Zn bioavailabilties of Mn and Zn sources for broilers (Li et al, 2004(Li et al, , 2005Huang et al, 2009Huang et al, , 2013Wang et al, 2012;Liu et al, 2013). In traditional multiple linear regression slope ratio methods, the purified or semipurified diets supplemented with mineral levels below requirements of animals were adopted and growth and Hb, etc., were used as evaluation indices , or the conventional diets supplemented with excessive but nontoxic mineral levels were adopted and mineral accumulations in target tissues were used as evaluation indices (Henry et al, 1989;Cao et al, 1996).…”

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The chemical characteristics of organic iron sources and their relative bioavailabilities for broilers fed a conventional corn–soybean meal diet1

Zhang

Lü

Luo

2016

Journal of Animal Science

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Twenty-four organic Fe sources were evaluated by polarographic analysis and via solubility in buffers (pH 5 and 2) and deionized water. Organic Fe sources included 6 Fe-Met complexes (Fe-Met), 10 Fe-Gly complexes, 1 Fe-Lys complex, 4 Fe proteinates, and 3 Fe-AA complexes (Fe-AA). Sources varied considerably in chemical characteristics. Chelation strengths (quotient of formation [Q] values) ranged from weak (Q = 1.08) to extremely strong strength (Q = 8,590). A total of 1,170 1-d-old Arbor Acres male broilers were randomly allotted to 6 replicate cages (15 chicks/cage) for each of 13 treatments in a completely randomized design involving a 4 × 3 factorial arrangement of treatments (4 Fe sources × 3 added Fe levels) plus a control with no added Fe. Dietary treatments included a corn-soybean meal basal diet (control; 55.8 mg Fe/kg) and the basal diet supplemented with 20, 40, or 60 mg Fe/kg as iron sulfate (FeSO∙7HO); an Fe-Met with weak chelation strength (Fe-Met W; Q = 1.37; 14.7% Fe); an iron proteinate with moderate chelation strength (Fe-Prot M; Q = 43.6; 14.2% Fe); or an iron proteinate with extremely strong chelation strength (Fe-Prot ES; Q = 8,590; 10.2% Fe). The growth performance, Fe concentrations, hematological indices, and activities and gene expressions of 2 Fe-containing enzymes in tissues of broilers at 7, 14, and 21 d of age were determined in the present study. Transferrin saturation in plasma on 14 d; bone Fe on d 7 and 14; liver Fe on d 7, 14, and 21; kidney Fe on d 14; succinate dehydrogenase activities in the liver on d 21 and in the kidney on d 7 and 21; mRNA levels in the kidney and heart on d 14; and mRNA levels in the liver and kidney on d 21 linearly increased ( < 0.05) as added Fe levels increased. However, differences in bioavailabilities among Fe sources were detected ( < 0.05) only for the mRNA levels in the liver and kidney on d 21. Based on slope ratios from the multiple linear regression of mRNA level in the liver or kidney of broilers on d 21 on daily dietary analyzed Fe intake, the bioavailabilities of Fe-Met W, Fe-Prot M, and Fe-Prot ES relative to iron sulfate (100%) were 129 ( = 0.18), 164 ( < 0.003), and 174% ( < 0.001) or 102 ( = 0.95), 143 ( = 0.09), and 174% ( < 0.004), respectively. These results indicated that the relative bioavailabilities of organic Fe sources were closely related to their Q values and organic Fe sources with greater Q values showed higher Fe bioavailabilities.

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Copper in Organic Proteinate or Inorganic Sulfate Form is Equally Bioavailable for Broiler Chicks Fed a Conventional Corn–Soybean Meal Diet

Liu

Lü

et al. 2012

Biol Trace Elem Res

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An experiment was conducted to investigate the bioavailability of organic copper (Cu) proteinate relative to inorganic Cu sulfate for broiler chicks fed a conventional corn-soybean meal basal diet. A total of 320 day-old Arbor Acres commercial male chicks were assigned to one of five treatments in a completely randomized design involving a 2 × 2 factorial arrangement with two levels of added Cu (125 or 250 mg Cu/kg) and two Cu sources (Cu proteinate and Cu sulfate) plus a control with no added Cu for an experimental phase of 42 days. Plasma and liver tissue samples were collected at both 21 and 42 days of age, and bile samples were also obtained at 42 days of age for Cu analyses. The Cu concentrations in liver and bile increased linearly (P < 0.001) on both days 21 and 42 as dietary Cu levels increased. No significant (P > 0.17) linear regression relationships were observed between plasma Cu concentrations on days 21 and 42 or log10 liver Cu concentration on day 21 and daily analyzed Cu intake. Therefore, based on the slope ratios from multiple linear regressions of log10 liver and bile Cu concentrations with daily analyzed Cu intake on day 42, when Cu sulfate was set as 100%, the estimated relative bioavailability values of Cu proteinate were 78.8% for log10 liver Cu concentration and 79.3% for log10 bile Cu concentration, respectively. There was no significant (P > 0.08) difference in bioavailability between Cu proteinate and Cu sulfate for broilers chicks in this experiment.

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Relative Bioavailability of Manganese Proteinate for Broilers Fed a Conventional Corn–Soybean Meal Diet

Cited by 27 publications

References 15 publications

Relative bioavailability of humate–manganese complex for broilers fed a corn–soya bean meal diet

Relative bioavailability of humate–manganese complex for broilers fed a corn–soya bean meal diet

The chemical characteristics of organic iron sources and their relative bioavailabilities for broilers fed a conventional corn–soybean meal diet1

Copper in Organic Proteinate or Inorganic Sulfate Form is Equally Bioavailable for Broiler Chicks Fed a Conventional Corn–Soybean Meal Diet

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