2002
DOI: 10.1034/j.1399-6576.2003.470115.x
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Remifentanil‐propofol vs. sufentanil‐propofol: optimal combinations in clinical anesthesia

Abstract: The present clinical trial conducted in thyroid surgery is consistent with previous computer-simulated opioid-propofol combinations with respect to intraoperative and recovery variables. Effect-site propofol ranges were, however, lower than expected.

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Cited by 30 publications
(15 citation statements)
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“…Therefore, a lowest dose of 0.75 mg kg 21 and a highest dose of 1.25 mg kg 21 were chosen in this study. In this study, the bolus dose of 2.5 mg kg 21 propofol was used because of synergistic action between narcotics and hypnotics [17]. Vecuronium was chosen for neuromuscular blockade as it is free from cardiovascular effects [18].…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, a lowest dose of 0.75 mg kg 21 and a highest dose of 1.25 mg kg 21 were chosen in this study. In this study, the bolus dose of 2.5 mg kg 21 propofol was used because of synergistic action between narcotics and hypnotics [17]. Vecuronium was chosen for neuromuscular blockade as it is free from cardiovascular effects [18].…”
Section: Discussionmentioning
confidence: 99%
“…The analgesic concentrations of opioid can affect the predictive performance of TCI by a significant reduction of the target propofol concentration needed to achieve hypnosis without affecting the BIS values. 9,13,25,26 Although the C e of sufentanil 0.2 ng/ml used in this study was far lower than that for the appearance of EEG depression 13 and sufficient to ensure hemodynamic stability without delayed recovery, 9 it could reduce the target propofol concentration for the maintenance of anesthesia. Third, the open TCI systems used in this study have two different pharmacokinetics, the Marsh and Schnider model.…”
Section: Discussionmentioning
confidence: 81%
“…29,30,31 Total Intravenous Anesthesia (TIVA) with Propofol is excellent due to its rapid onset, rapid recovery, antiemetic property and synergistic action with fentanyl. 32,33 CONCLUSIONS: The purpose of pre-operative preparation of the patient for thyroid surgery includes investigations to confirm the diseases of thyroid and prepare the surgeon to predict and be cautious regarding post-operative complications. Both the surgeon and the patient should be prepared well to correct the multiple complications with proper maneuvers.…”
Section: Discussionmentioning
confidence: 99%