Renal Clear Cell Carcinoma Acrometastasis. An Unusual Terminal Condition

Hernández‐Cortés, Pedro; Caba-Molina, Mercedes; Gómez-Sánchez, R.; Rios-Peregrina, Rosa M.

doi:10.1007/s12593-014-0127-5

Cited by 7 publications

(7 citation statements)

References 16 publications

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“…He underwent a carpectomy and survived one year after AM diagnosis. Other authors have reported direct or indirect traumatisms before the development of AM, confirming the pathophysiological hypothesis suggesting that trauma plays an important role [128][129][130].…”

Section: Pathophysiologysupporting

confidence: 71%

Acrometastases to the Hand: A Systematic Review

et al. 2021

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Background and Objectives: The term acrometastases (AM) refers to secondary lesions sited distally to the elbow and knee, representing 0.1% of all bony metastases. By frequency, pulmonary cancer and gastrointestinal and genitourinary tract neoplasms are the most responsible for the reported AM. Improvements in oncologic patient care favor an increase in the incidence of such rare cases. We performed a systematic review of acrometastases to the hand to provide further insight into the management of these fragile patients. We also present a peculiar case of simultaneous acrometastasis to the ring finger and pathological vertebral fracture. Material and Methods: A literature search according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement was conducted using the PubMed, Google Scholar, and Scopus databases in December 2020 on metastasis to the hand and wrist, from 1986 to 2020. MeSH terms included acrometastasis, carpal metastasis, hand metastasis, finger metastasis, phalangeal metastasis, and wrist metastasis. Results: In total, 215 studies reporting the follow-up of 247 patients were analyzed, with a median age of 62 years (range 10–91 years). Overall, 162 out of 247 patients were males (65.6%) and 85 were females (34.4%). The median reported follow-up was 5 months (range 0.5–39). The median time from primary tumor diagnosis to acrometastasis was 24 months (range 0.7–156). Acrometastases were located at the finger/phalanx (68.4%), carpal (14.2%), metacarpal (14.2%), or other sites (3.2%). The primary tumors were pulmonary in 91 patients (36.8%). The average interval from primary tumor diagnosis to acrometastasis varied according to the primary tumor type from 2 months (in patients with mesenchymal tumors) to 64.0 months (in patients with breast cancer). Conclusions: Acrometastases usually develop in the late stage of oncologic disease and are associated with short life expectancy. Their occurrence can no longer be considered rare; physicians should thus be updated on their surgical management and their impact on prognosis and survival.

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Section: Pathophysiologysupporting

confidence: 71%

Acrometastases to the Hand: A Systematic Review

et al. 2021

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“…Los sitios del dedo/falange, carpiano y metacarpiano son los sitios prevalentes de AM, porque los factores quimiotácticos liberados después de traumatismos continuos estimulan la liberación de prostaglandinas, que favorecen la adhesión de las células tumorales 14 . También se han informado traumatismos directos o indirectos antes del desarrollo de la AM, lo que confirma la hipótesis fisiopatológica que sugiere que el trauma juega un papel importante [15][16][17] . Según Umana et al en su revisión sistemática de 247 pacientes, la media de edad fue de 62 años, el 65.6% eran varones, la mediana desde el diagnóstico del tumor primario hasta la acrometástasis fue de 24 meses, la localización en el dedo (68.4%), el carpo (14.2%) y metacarpo (14.2%) 3 .…”

Section: Discussionunclassified

Acrometástasis de mano como recaída de adenocarcinoma de cérvix: una entidad rara. Revisión de la literatura

Robles-Díaz¹

2022

GAMO

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La acrometástasis de mano tiene una incidencia baja, pero si el origen es cáncer de cuello uterino, es sumamente rara. Su presentación marca un pronóstico desfavorable para la paciente. El tratamiento va a depender de si se encuentra en el escenario de oligometástasis o no, y de si su presentación es de novo o como recaída de enfermedad. Se revisa el tema a propósito del caso en una mujer de 51 años, con cáncer de cuello uterino tratada quirúrgicamente, que desarrolla acrometástasis de mano y recurrencia en cúpula vaginal. Se le propone someterse a la amputación de falange distal y terapia sistémica.Palabras clave: Acrometástasis. Cáncer de cérvix. Metástasis rara. Metástasis de la neoplasia. Acrometastasis of the hand as a relapse of adenocarcinoma of the cervix: A rare entity. Literature review

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“…The prevalence of tongue metastases is estimated to be 0.17% 3. Similarly, metastasis to the distal extremities is also rare and represents <0.2% of all metastatic lesions 4. Although single skin lesions may be treated with either surgical resection or radiotherapy in some cases, metastatic lesions typically require systemic therapy with an angiogenesis/multiple kinase inhibitor 5 6.…”

Section: Descriptionmentioning

confidence: 99%