Renewable superwettable biochip for miRNA detection

Wu, Tingting; Xu, Tailin; Chen, Yanxia; Yang, Yuemeng; Xu, Li-Ping; Zhang, Xueji; Wang, Shutao

doi:10.1016/j.snb.2017.11.109

Cited by 45 publications

(18 citation statements)

References 49 publications

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“…These properties derived from superwettability have been harnessed in many applications including photovoltaics, organic light‐emitting diodes (OLEDs), cell capture, and lab‐on‐chip devices . Here, we limit our discussion to the process made over the past 3 years in emerging applications of topological textured surfaces including optoelectronics, droplet manipulation, microreactor biochemical assays, and medical coatings …”

Section: Applicationsmentioning

confidence: 99%

“…On such a surface, a suspended solution droplet evaporates, and the solute gradually becomes concentrated with no loss due to the nonwetting property of the surface . After evaporation, the solution drop collapses and the molecules precipitate on the micro/nanostructures of the superhydrophobic surface for further detection . The combination of superhydrophobic surfaces and nanoplasmonic sensors ( Figure a–h) enables the single‐molecule detection of chemicals and biomolecules at femtomolar (10 −15 mol L −1 ) or attomolar (10 −18 mol L −1 ) levels (Figure i,j).…”

Section: Applicationsmentioning

confidence: 99%

“…The solute in aqueous microdroplet arrays can be further enriched by condensation, while these droplets are pinned in the hydrophilic regions . As such, high‐throughput droplet‐based chemical sensing of heavy metal ions, bacteria assays, biochemical assays, biocatalytic reactions, and multiplex bioassays can be performed …”

Section: Applicationsmentioning

confidence: 99%

See 2 more Smart Citations

Bioinspired Superwettability Micro/Nanoarchitectures: Fabrications and Applications

Kong

Luo

Zhao

et al. 2019

Adv Funct Materials

150

104

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Biological systems have evolved over billions of years to develop wetting strategies for advantageous structure-property-performance relations that are crucial for their survival. The discovery of these intriguing relationships has inspired tremendous efforts to investigate the micro/nanoscale features of naturally occurring structures with superwettability. Researchers have since developed new methods and techniques to construct artificial materials that mimic natural structures and functionalities. Here, a brief review of natural hierarchical architectures with liquid repellent properties is presented, and the critical underlying mechanism is summarized with an emphasis on the micro/nanoscopic architectures. The state-of-the-art micro/nanofabrication techniques for creating bioinspired hierarchical superwettability structures that are categorized by random and exquisite features are also reviewed, followed by an overview of their emerging applications, with special attention to biomedical-related fields. The development of fabrication techniques enhances capabilities relative to those of living systems, paving the way toward advanced structural materials with superior functions and unprecedented characteristics for potential applications. Figure 1. Natural superwettable surfaces. Scanning electronic microscopy (SEM) images demonstrate the surface micro/nanostructures of a) lotus leaf, [4] b) Salvinia molesta, [115] c) cicada wings, [109] d) mosquito eye, [37] e) cactus spines, [110] f) desert beetle, [2] g) water strider, [5] h) springtail skin, [145] and i) pitcher plant. [50] The examples represent a range of different intelligent surfaces that exist in nature. Reproduced with permission. [4]

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Section: Applicationsmentioning

confidence: 99%

Section: Applicationsmentioning

confidence: 99%

See 1 more Smart Citation

Bioinspired Superwettability Micro/Nanoarchitectures: Fabrications and Applications

Kong

Luo

Zhao

et al. 2019

Adv Funct Materials

150

104

View full text Add to dashboard Cite

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“…Until now, SPW had been extensively explored as an effective high‐throughput platform for bioassay and biosensing . For example, Wang group developed SPW for various biosensing, such as sensitive nucleic acid detection based on condensing‐enrichment effect, microgravity biosensing and electrochemical detection toward cancer biomarkers . Noticeably, the specific micro‐/nanostructure of the (super)wetting domains can be helpful for the designed detections.…”

Section: Applicationsmentioning

confidence: 99%

Micro‐/Nanostructured Interface for Liquid Manipulation and Its Applications

Duan

Zheng

Zhao

et al. 2019

Small

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Understanding the relationship between liquid manipulation and micro‐/nanostructured interfaces has gained much attention due to the wide potential applications in many fields, such as chemical and biomedical assays, environmental protection, industry, and even daily life. Much work has been done to construct various materials with interfacial liquid manipulation abilities, leading to a range of interesting applications. Herein, different fabrication methods from the top‐down approach to the bottom‐up approach and subsequent surface modifications of micro‐/nanostructured interfaces are first introduced. Then, interactions between the surface and liquid, including liquid wetting, liquid transportation, and a number of corresponding models, together with the definition of hydrophilic/hydrophobic, oleophilic/olephobic, the definition and mechanism of superwetting, including superhydrophobicity, superhydrophilicity, and superoleophobicity, are presented. The micro‐/nanostructured interface, with major applications in self‐cleaning, antifogging, anti‐icing, anticorrosion, drag‐reduction, oil–water separation, water collection, droplet (micro)array, and surface‐directed liquid transport, is summarized, and the mechanisms underlying each application are discussed. Finally, the remaining challenges and future perspectives in this area are included.

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“…Based on this functional surface, the detection of microRNA‐141 could be achieved at an extreme low limit of 1 pM, which was also successful even in real samples. Wang's group fabricated a series of superwettable microchips, possessing the abilities of detecting the biomolecules miRNA‐141, 103 DNA, 104 free prostate‐specific antigen 105 with respective detection limit of 88 pM, 2.3 × 10 −16 M, 10 fg/mL.…”

Section: Bioinspired Superwetting Surfaces For Biosensingmentioning

confidence: 99%

Bioinspired superwetting surfaces for biosensing

Zhu

Huang

Lou

et al. 2020

VIEW

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Inspired by nature, scientists and researchers have studied the wetting behaviors on various creatures and mimicked their structures to fabricate diverse functional superwetting materials. As one kind of emerging application, the bioinspired superwettable surfaces used for biosensing have been aroused wide interests. In this review, we summarized the recent developments of bioinspired superwettable surfaces in the field of biosensing. In the first part, superwettable creatures in nature, namely, superhydrophobic self-cleaning lotus leaf, high-adhesion superhydrophobic rose petal, amphiphobic springtail, patterned wetting desert beetles, slippery pitcher plant, were introduced. In sequence, we successively described the special wetting models of superhydrophobicity, superamphiphobicity, responsive wettability, patterned wettability, and slipperiness. Then, biosensing applications based on the respective patterned wettable, superhydrophobic, responsive wettable, and slippery substrates that were combined with the common detection approaches (colorimetry, fluorescence, surface-enhanced Raman scattering (SERS), electrochemistry) were shown in detailed. At last, an insight of remaining challenges and future development for bioinspired superwetting materials applied in biosensing was provided.

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Renewable superwettable biochip for miRNA detection

Cited by 45 publications

References 49 publications

Bioinspired Superwettability Micro/Nanoarchitectures: Fabrications and Applications

Bioinspired Superwettability Micro/Nanoarchitectures: Fabrications and Applications

Micro‐/Nanostructured Interface for Liquid Manipulation and Its Applications

Bioinspired superwetting surfaces for biosensing

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