Reproduction and gynaecological manifestations in women with primary Sjögren's syndrome: a case‐control study

Haga, Hans‐Jacob; Gjesdal, Clara Gram; Irgens, Lorentz M.; Østensen, Monika

doi:10.1080/03009740510017959

Cited by 54 publications

(26 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…26 Second, female patients with sicca syndrome might suffer from local irritation of the urinary bladder due to vaginal sicca. 6,27 Finally, Tishler et al 10 reported that patients with RA and secondary SS had a higher prevalence of urinary tract infections, which could also be a contributing factor to overactive bladder.…”

Section: Discussionmentioning

confidence: 98%

Multifactorial causes of irritating bladder symptoms in patients with sjögren's syndrome

Lee

Dong

Chen

et al. 2010

Neurourology and Urodynamics

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 98%

Multifactorial causes of irritating bladder symptoms in patients with sjögren's syndrome

Lee

Dong

Chen

et al. 2010

Neurourology and Urodynamics

View full text Add to dashboard Cite

show abstract

“…Hyperactive bladder and increased fluid intake related with chronic dry mouth may be the underlying causes (19). Local irritation of the bladder that is attributed to vaginal dryness in the patients with RA and SS could also contribute to the disease process (5,20). Nephritis and/or nephropathy-induced conditions, including urinary tract infections, hematuria, and pyuria, can also exacerbate LUTS (19).…”

Section: Discussionmentioning

confidence: 99%

“…AUASI questionnaire includes seven questions to query the presence of a possible irritative (frequency, urgency, and nocturia) and obstructive (incomplete emptying, decrease in flow rate, and straining) urinary symptoms. A scoring system was utilized to classify the degree of the symptoms as mild (0-7), moderate (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19), or severe (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35). The final item of the AUASI form investigates the impact of urinary symptoms on QoL, and this entity is scored between 0 and 6 (10).…”

Section: Methodsmentioning

confidence: 99%

Frequency of Lower Urinary Tract Symptoms and Effects on Quality of Life in Women with Rheumatoid Arthritis

Aras¹,

Aras²,

İçağasıoğlu³

et al. 2015

Turk J Phys Med Rehab

View full text Add to dashboard Cite

Objective: To investigate the frequency of lower urinary tract symptoms (LUTS) in women with rheumatoid arthritis (RA) and to evaluate its possible effects on quality of life (QoL). Material and Methods: A total of 104 women diagnosed with RA, who were aged between 30 and 60 years, and 82 healthy women were included in this study. We used the American Urological Association symptom index as the gold criteria in the evaluation of LUTS and QoL. Hospital Anxiety and Depression Scale was used to evaluate anxiety/depression levels, whereas disease activity scale (DAS-28) and Health Assessment Questionnaire (HAQ) were used to determine the disease activity levels. Results: There was no statistical difference between the two groups by means of age range. There was a prominent difference in LUTS frequency between the groups and moderate to severe symptoms were higher in women with RA. QoL measurements were also significantly lower in this group (p<0.01). There was a positive relationship between anxiety and LUTS and significantly positive relationship between depression and LUTS measurement (p<0.01). There was a positive relationship between depression and QoL; however, there was no relationship between anxiety and QoL measurements. Although there was no relationship between LUTS and DAS-28, significant relationship was found between LUTS and HAQ. There was no relationship between QoL and DAS-28; however, there was a significant relationship between QoL and HAQ (p<0.01). Conclusion: LUTS were more frequent in women with RA; furthermore, QoL was low. Furthermore, these symptoms can be related with anxiety and depression. Moderate and severe symptoms observed in women with RA are frequently related with HAQ.

show abstract

“…Patients with pSS reported more gynecological problems than controls, including vaginal sicca symptoms, endometriosis, several episodes of amenorrhoea, and menorrhagia/metrorrhagia [55]. Vasculitis, as demonstrated by the presence of perivascular infiltrations in vaginal tissues from these patients, rather than glandular dysfunction, seems to account for the vaginal dryness, as vaginal lubrication is mainly related to transudate from vaginal walls [54].…”

Section: Obstetrical and Gynecological Complicationsmentioning

confidence: 98%

Conventional Therapy of Sjogren’s Syndrome

Mavragani

Moutsopoulos

2007

Clinic Rev Allerg Immunol

View full text Add to dashboard Cite

Sjogren's syndrome (SS) is a chronic autoimmune disorder affecting mainly middle-aged women. It is characterized by lymphocytic infiltration and destruction of the exocrine glands (mainly the salivary and lacrimal glands), resulting in dry mouth and eyes. Symptoms of SS are chronic and sometimes devastating, compromising the quality of life at a major extent. Despite its autoimmune nature, evidence for the use of immunosuppressive agents, which are the mainstay of therapy of diseases of autoimmune origin, is limited. Keratoconjunctivitis sicca (KCS), the main ocular manifestation of SS, is managed with tear substitutes, as well as local and systemic stimulators of tear secretion and supportive surgical procedures. Management of oral manifestations includes intense oral hygiene, prevention and treatment of oral infections, use of saliva substitutes, and local and systematic stimulation of salivary secretion. Cholinergic agents, such as pilocarpine and cevimeline are the cornerstone of current therapy in SS. Corticosteroids, cyclophoshamide, and nucleoside analogues are reserved for severe extraglandular manifestations of SS. The role of anti-B-cell therapy is a promising option for glandular and extraglandular manifestations of the disease, as well as for the management of SS-associated lymphoma.

show abstract

Reproduction and gynaecological manifestations in women with primary Sjögren's syndrome: a case‐control study

Abstract: Patients with pSS reported more gynaecological problems than controls, including vaginal sicca symptoms, endometriosis, several episodes of amenorrhoea, and menorrhagia/metrorrhagia.

Cited by 54 publications

References 12 publications

Multifactorial causes of irritating bladder symptoms in patients with sjögren's syndrome

Multifactorial causes of irritating bladder symptoms in patients with sjögren's syndrome

Frequency of Lower Urinary Tract Symptoms and Effects on Quality of Life in Women with Rheumatoid Arthritis

Conventional Therapy of Sjogren’s Syndrome

Contact Info

Product

Resources

About