2016
DOI: 10.1016/j.jdiacomp.2016.06.011
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Reproductive factors and risk of type 2 diabetes in an occupational cohort of Chinese women

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Cited by 23 publications
(35 citation statements)
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“…Consistent with previous studies showing that late menopause can increase the diabetes risk, the present findings also showed that the age at natural menopause affected type 2 diabetes risk even after adjustment for age, BMI and other potential confounders, though the cut‐off points for menopausal age differed from the previous studies. Another two studies involving menopausal age ≥53 years, which was in line with our cut‐off point for later age at menopause in the present study, showed that the association was not statistically significant after multivariable adjustment.…”
Section: Discussionsupporting
confidence: 91%
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“…Consistent with previous studies showing that late menopause can increase the diabetes risk, the present findings also showed that the age at natural menopause affected type 2 diabetes risk even after adjustment for age, BMI and other potential confounders, though the cut‐off points for menopausal age differed from the previous studies. Another two studies involving menopausal age ≥53 years, which was in line with our cut‐off point for later age at menopause in the present study, showed that the association was not statistically significant after multivariable adjustment.…”
Section: Discussionsupporting
confidence: 91%
“…Both the European Prospective Investigation into Cancer and Nutrition (EPIC)-InterAct study in Europe 11 and Dongfeng-Tongji cohort study in China 12 have found that early menopause is associated with a greater risk of type 2 diabetes. Several other studies from the USA and China [13][14][15] reported that women with late menopause had an increased diabetes risk. Meanwhile, three studies from Italy, Japan and China found no effects of age at menopause on diabetes risk [16][17][18] .…”
Section: Introductionmentioning
confidence: 96%
“…A meta-analysis study showed that early menarche was correlated with a higher risk of type 2 diabetes 11 , whereas hormone-replacement therapy in postmenopausal women was linked to a reduced risk 15 . Although the evidence is mixed, early menopause 5,6 , long or irregular menstrual cycle [16][17][18][19] and postmenopausal status 6,10 have been linked to a higher risk of type 2 diabetes. Here, however, we did not find any associations between these factors and type 2 diabetes risk.…”
Section: Discussionmentioning
confidence: 99%
“…All were observational studies, and 1 additionally included a Mendelian randomisation analysis [13]. Nine studies were conducted among white individuals [18,19,24,[26][27][28][29][30][31], 13 studies among Asian individuals (Chinese, Bangladeshi, Korean, and Japanese) [12,13,20,21,[32][33][34][35][36][37][38][39][40], and 6 studies among multi-ethnic populations (white, Hispanic, Asian, African-American, and Latino) [17,[41][42][43][44][45]. Fourteen studies examined prevalent T2D [13,18,19,24,26,27,30,34,[36][37][38][39]43,45], 2 prevalent IGT [21,32], 3 prevalent T2D and IGT [28,33,35], 8 incident T...…”
Section: Study Characteristicsmentioning
confidence: 99%
“…The definitions of T2D and IGT varied across studies, and 4 studies excluded participants with potential type 1 diabetes based on age at diagnosis [24,26,42,43]. Adiposity indicators were adjusted for in 25 studies and were mostly BMI alone (n = 19) [17][18][19][20][21][26][27][28][29][30][31]35,37,[39][40][41][43][44][45], followed by both BMI and waist circumference (n = 4) [12,34,36,42], waist circumference alone (n = 1) [32], and body composition (n = 1) [24]. Early menarche was defined as AAM < 12 years in 9 studies [17,24,[29][30][31]38,[41][42][43] and <14 years in 13 studies [12,18,20,21,[32][33][34][35][36]…”
Section: Study Characteristicsmentioning
confidence: 99%