Research concerning fabrication of fibrous osteoconductive plga/hap nanocomposite material using the method of electrospinning from polymer solution

Krucińska, Izabella; Boguń, Maciej; Chrzanowska, Olga; Chrzanowski, M.; Król, Paulina

doi:10.2478/v10304-012-0027-3

Cited by 4 publications

(4 citation statements)

References 45 publications

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“…The incorporation of an element like HAp does not only lead to a better osseointegration, but also modifies different properties of the matrix in which it was added. 23 As an example, in the study of Ito and co-workers 134 the development of a poly(3-hydroxybutyrate-co-3-hydroxyvalerate (PHBV) mat by electrospinning coated with HAp was reported. The resulting electrospun PHBV film was hydrophobic; however, after HAp deposition the surface became hydrophilic.…”

Section: Bones Tissuesmentioning

confidence: 99%

“…9 In case of bone tissue, a key factor to improve regeneration is the incorporation of materials that promote osseointegration, such as hydroxyapatite and collagen. [10][11][12][13][14][15][16][17][18][19][20][21][22][23] On the other hand, in the case of muscles, besides the incorporation of bioactive groups, the orientation of mat fibers is a key goal to approach a similar structure to ECM. [24][25][26] The same idea is applied to tendon tissue engeniering.…”

Section: Introductionmentioning

confidence: 99%

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Electrospun Nanofibrous Mats: From Vascular Repair to Osteointegration

Ribba¹,

Parisi²,

D’Accorso³

et al. 2014

j biomed nanotechnol

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Electrospinning is a versatile technique for generating a mat of continuous fibers with diameters from a few nanometers to several micrometers. The diversity of electrospinnable materials, and the unique features associated with electrospun fibers make this technique and its resultant structures attractive for applications in the biomedical field. This article presents an overview of this technique focusing on its application for tissue engineering. In particular, the advantages and disadvantages of using an electrospinning mat for biomedical applications are discussed. It reviews the different available electrospinning configurations, detailing how the different process variables and material types determine the obtained fibers characteristics. Then a description of how nanofiber based scaffolds offer great promise in the regeneration or function restoration of damaged or diseased bones, muscles or nervous tissue is reported. Different methods for incorporating active agents on nanofibers and controlling their release mechanisms are also reviewed. The review concludes with some personal perspectives on the future work to be done in order to include electrospinning technique in the industrial development of biomedical materials.

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Section: Bones Tissuesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrospun Nanofibrous Mats: From Vascular Repair to Osteointegration

Ribba¹,

Parisi²,

D’Accorso³

et al. 2014

j biomed nanotechnol

View full text Add to dashboard Cite

show abstract

“…Among the various methods ofPLAfiber formation [24][25][26][27][28] (molten polymer extrusion, dry spinning from solution, electrospinning), wet spinning from solution has a number of advantages. Importantly, it eliminates the risk of thermal degradation of the polymer, in contrast to molten polymer extrusion, in which the polymer material must meet strict requirements, including stoichiometric composition and crystalline structure (determining the melting temperature), as well as low moisture content.…”

Section: Introductionmentioning

confidence: 99%

Glycolide/L-Lactide Copolymer (PGLA) Fibers Formed by Wet Spinning from Solution and Modified with Ceramic Nanoadditives

Król

Szparaga

Mikołajczyk

et al. 2018

Autex Research Journal

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The paper presents the results of research into glycolide/L-lactide copolymer (PGLA) fiber formation by wet spinning from solution. The selected process conditions led to fibers with a specific tensile strength of more than 35 cN/tex. Furthermore, ceramic nanoadditives such as hydroxyapatite (HAp) and β-tricalcium phosphate (β-TCP) were used to obtain fibers with osteoconductive properties. It was found that the ceramic nanoadditives reduced the specific strength of fibers (to 24 cN/tex for β-TCP and to 27 cN/tex for HAp). The paper also presents wide-angle X-ray scattering (WAXS) evaluation of the supramolecular structure of the fibers as well as their porosity parameters and microscopic structure. The obtained fibers were woven into a textile fabric with potential applications in biomedical engineering.

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“…weaving). This article is a contribution to solving this issue and thus adds findings from previously published works in the field of theoretical and experimental analysis of the mechanical properties of nanofibres [see [1][2][3] or the method of their production [see [4][5][6][7][8][9][10], which affects the mechanical properties of nanofibres.…”

Section: Introductionmentioning

confidence: 99%

Mechanical Properties Of Traditional And Nanofibre Textiles

Ursíny

Bílek

Moučková

et al. 2015

Autex Research Journal

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This study deals with a comparison of mechanical properties of a conventional yarn and a textile from nanofibres. The conventional yarn represents the textile objects with high degree of orientation of fibres and the textile from nanofibres represents the textile objects with low degree of orientation of fibres. The theoretical section is concerned with the issue of internal structure of plied yarn and resulting differences in the orientation and straightening of fibres and in utilisation of deformation properties of fibres in comparison to the referred nano textile. The experimental section describes the manner of realisation of both static and dynamic tests of conventional yarn and strips of nanofibres. The results show differences in the mechanical properties of conventional yarn and textile strip from nanofibres under static and dynamic loading conditions. The processing technology of conventional yarn has been verified in the long term. But textiles from nanofibres are a relatively new material and mechanical properties of the detected differences point out possible problems with their behaviour during standard technological processes.

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Research concerning fabrication of fibrous osteoconductive plga/hap nanocomposite material using the method of electrospinning from polymer solution

Cited by 4 publications

References 45 publications

Electrospun Nanofibrous Mats: From Vascular Repair to Osteointegration

Electrospun Nanofibrous Mats: From Vascular Repair to Osteointegration

Glycolide/L-Lactide Copolymer (PGLA) Fibers Formed by Wet Spinning from Solution and Modified with Ceramic Nanoadditives

Mechanical Properties Of Traditional And Nanofibre Textiles

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