Residents’ knowledge in transfusion medicine and educational programs: A pilot study

Bouchrim, S.-A. Ait; Haddad, Antoine; Assi, Tarek; Oriol, P.; Guyotat, Denis; Bois, Christophe; Garraud, Olivier

doi:10.1016/j.tracli.2019.10.002

Cited by 13 publications

(12 citation statements)

References 52 publications

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“…Uprkos uvođenju testova za dijagnostikovanje ova dva tipa hepatitisa, nije bila retka pojava posttransfuzionog hepatitisa (PTH), kao i sporadično stečenog hepatitisa prouzrokovanog ne samo HAV-om ili HBV-om, nego i nekim drugim tipovima virusa. Zbog toga je Nacionalni Institut za zdravlje SAD predložio da virus hepatitis tipa nonA/nonB (NANBH) bude naziv za oboljenje prouzrokovano ovim tipovima virusa [2,3,8,9]. U vezi sa tim, ustanovljeno je da postoje enteralni i parenteralni tip NANBH.…”

Section: Uvodunclassified

“…U vezi sa tim, ustanovljeno je da postoje enteralni i parenteralni tip NANBH. Uzročnik ente-ralnog NANBH je virus E (HEV), a parenteralnog hepatitisa je HCV [2,3,[8][9][10].…”

Section: Uvodunclassified

“…Ispitivanje prisustva HBsAg u serumu osoba se izvodi enzimoimunim testovima -EIA, ili još nazvanim i ELISA testovima ("Enzyme Linked Immunoapsorbent Essay"), a pored toga može se dokazati u citoplazmi hepatocita pomo-ću imunoelektronskog mikroskopiranja (IEM) [2][3][4][5][6][8][9][10][11][12][13][14][15][16]. Na osovu dosadašnjih saznanja [1][2][3][4][5][6]11] poznato je da se u centru viriona nalazi tzv.…”

Section: Diskusijaunclassified

“…Almeida sa saradnicima, prvi je dokazao HBcAg prilikom lize viriona deterdžentima [9,11,14]. HBcAg se može detektovati u jedru a ponekad i u citoplazmi hepatocita pomoću IEM [2][3][4][5][6][8][9][10][11]. Treći antigen HBV nazvan je HBeAg-om, solubilan je i za njega se smatra da je produkt katalize (cepanja) HBcAg-a.…”

Section: Diskusijaunclassified

“…Pored opisanog "klasičnog" HBV, poznata je i posebna varijanta virusa, nazvana HBV-2 i njega karakteriše da ne indukuje sintezu antitela anti-HBc i anti-HBe. Varijanta HBV-2 javlja se kao rezultat strukturnih promena HBV-a, najverovatnije da se radi o promena u sekvenci HBcAg-a [8][9][10][11][20][21][22].…”

Section: Diskusijaunclassified

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Blood-borne disease markers analysis, creating testing algorithms and application of preventive measures

Stanković¹,

Gojkovic-Bukarica²,

Trišović³

et al. 2019

NČ urgent medic Halo 194

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SAŽETAK Uvod/cilj Najčešće krvlju prenosive bolesti ili transfuzijske transmisivne infekcije (TTI) su hepatitis tipa B i C i virus humane imunodeficijencije (HIV). Brojnim testovima može se dokazati njihovo prisustvo u krvi indirektnim (prisustvo antitela-ELISA i CLIA) ili direktnim putem (prisustvo genoma virusa NAT PCR i LCR). Cilj rada je analiza testiranja na markere krvlju prenosivih bolesti kod trudnica, pacijenata koji se pripremaju za planirane hirurške procdure i osobe sa rizičnim ponašanjem na prisustvo virusa (HBs Ag, anti-HCV i anti-HIV) sprovedenog u Gradskom zavodu za javno zdravlje u Beogradu i upoznavanje sa preventivnim merama za njihovo suzbijanje. Metod rada U dvogodišnjoj studiji testirano je 11.983 trudnica i 934 osoba sa rizičnim ponašanjem. Preliminarno testiranje na HBs Ag, antitela anti-HCV i anti-HIV, vršeno je ELISA testom treće generacije. Preliminarno pozitivni uzorci krvi ponovno su testirani istim testom iz novog uzorka, nakon 10-14 dana od utvrđene preliminarne pozitivnosti na ispitivane markere TTI. Kod ponovno pozitivnih uzoraka krvi rađen je potvrdni "Western Blot" test za određivanje antitela u humanom serumu ili plazmi, na markere TTI. Uzorci krvi pozitivni na potvrdnom testu na ispitivane markere TTI, prihvaćeni su kao potvrdno HBs Ag pozitivni, potvrdno anti-HCV reaktivni i potvrdno anti-HIV reaktivni. Rezultati Od ukupno testiranih trudnica bilo je 152 (1,27%) preliminarno reaktivnih, 38 potvrdno pozitivnih na HBsAg (0,32%) i 114 (0,95%) lažno reaktivnih na HBsAg; 123 (1,03%) preliminarno reaktivnih na anti-HCV, 35 potvrdno pozitivnih trudnica na antitelo anti-HCV (0,29%) i 88 (0,74%) lažno pozitivnih na HCV; i 15 (0,13%) preliminarno reaktivnih, 5 trudnica potvrdno pozitivnih na antitelo anti-HIV (0,04%) i 10 (0,09%) lažno reaktivnih anti-HIV. Od 934 testirane osobe sa rizičnim ponašanjem detektovano je 36 (3,85%) preliminarno reaktivnih na HBs Ag, 28 (2,99%) potvrdno pozitivnih na HbsAg i 8 (0,86%) lažno reaktivnih HBsAg; 38 (4,07%) preliminarno reaktivnih anti-HCV, 33 (3,53%) potvrdno pozitivnih na anti-HCV i 5 (0,54%) lažno reaktivnih na anti-HCV, kao i 10 (1,07%) preliminarno anti-HIV reaktivnih, 9 (0,96%) anti-HIV potvrdno pozitivnih i jedna (0,11%) osoba lažno-reaktivno na anti-HIV sa rizičnim ponašanjem. Zaključak Naše ispitivanje pokazuje veću prevalencu na HbsAg, anti-HCV i anti-HIV kod osoba sa rizičnim ponašanjem u odnosu na trudnice, ako i veću razliku u nalazu lažno reaktivnih rezultata kod trudnica, u odnosu na osobe rizičnog ponašanja. Preventivne mere sastojale bi se u edukaciji stanovništva o putevima širenja krvlju prenosivih bolesti, njihovoj prevenciji, testiranju krvi i krvnih produkata testovima najnovije generacije i pravilnom izvođenju medicinskih intervencija uz poštovanje principa asepse i antisepse. Ključne reči: markeri, krvlju prenosive bolesti, algoritmi, preventivne mere.

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Section: Uvodunclassified

“…U vezi sa tim, ustanovljeno je da postoje enteralni i parenteralni tip NANBH. Uzročnik ente-ralnog NANBH je virus E (HEV), a parenteralnog hepatitisa je HCV [2,3,[8][9][10].…”

Section: Uvodunclassified

Section: Diskusijaunclassified

See 3 more Smart Citations

Blood-borne disease markers analysis, creating testing algorithms and application of preventive measures

Stanković¹,

Gojkovic-Bukarica²,

Trišović³

et al. 2019

NČ urgent medic Halo 194

View full text Add to dashboard Cite

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Assessment of Transfusion Practices Among Doctors During COVID-19 Pandemic Using Questionnaire-Based Survey

Khatiwada

Chaurasia

Patidar

et al. 2022

Indian J Hematol Blood Transfus

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During COVID-19 pandemic, many doctors were redirected from various disciplines for care of COVID-19 patients. A survey was conducted among doctors involved, to assess transfusion practices during the pandemic. To assess the knowledge, attitude, and practices of blood transfusion among doctors involved in care of COVID-19 patients. A cross-sectional survey using an online questionnaire (Google form) was used to assess knowledge and need of transfusion, attitude towards modifications in transfusion process, and practices during pandemic. Analysis was done among subgroups based on experience (designation), user type (speciality) and frequency of blood usage in parent department. Of 1900 invitations, 437 responses were received from resident doctors and faculty members across various disciplines. Of these, 354(81%) participants were included in analysis. Mean knowledge score was 6.2, majority 297(83.9%) had adequate knowledge scores (≥ 5 of total 12). Knowledge levels were higher among frequent blood users. Positive attitude towards changes in transfusion process was observed in 72.9% participants with similar scores in subgroups. Practice was assessed in 222(62.7%) participants. Mean practice score was 6.9, wherein 57.7% participants had optimal scores (≥ 7 of total 14). Positive correlation was observed between attitude and practice, unlike knowledge and practice. Although most participants had demonstrated adequate transfusion knowledge levels and positive attitude, transfusion practices during pandemic were affected mainly due to shortage of blood components and modifications in transfusion requisition process due to stringent COVID-19 containment measures. Thus, indicating need for improvement in the basic understanding of the transfusion process. Supplementary Information The online version contains supplementary material available at 10.1007/s12288-022-01613-2.

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Hospital Medicine Providers’ Transfusion Knowledge: A Survey Study

Halford

Pinheiro

Haspel

2021

Transfusion Medicine Reviews

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Residents’ knowledge in transfusion medicine and educational programs: A pilot study

Cited by 13 publications

References 52 publications

Blood-borne disease markers analysis, creating testing algorithms and application of preventive measures

Blood-borne disease markers analysis, creating testing algorithms and application of preventive measures

Assessment of Transfusion Practices Among Doctors During COVID-19 Pandemic Using Questionnaire-Based Survey

Hospital Medicine Providers’ Transfusion Knowledge: A Survey Study

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