“…The recruitment and migration of inflammatory cells at sites of mucosal inflammation involve a variety of adhesion molecules [1]. Nonallergic chronic sinusitis is characterized by purulent paranasal sinus effusion and persistent nasal discharge with numerous emigrated neutrophils [2, 3, 4, 5, 6, 7, 8, 9], in additon to the accumulation of eosinophils in the tissue [5, 10, 11, 12, 13]. Tokushiga et al [14]proposed that IL–1β induces the expression of both intercellular adhesion molecule–1 (ICAM–1) and E–selectin on ECs, presumably leading to neutrophil infiltration.…”