Retinal Vascular Disease

Kanski, Jack J.; Bowling, Brad

doi:10.1016/b978-0-7020-4093-1.00013-6

Cited by 18 publications

(34 citation statements)

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“…Alterations in glucose metabolism lead to changes in the capillary walls of retinal vessels. This leads to breakdown of blood retinal barrier causing haemorrhages and seepage of exudates, which in turn present as detectable retinal thickening in OCT. [13][14][15] In contrast to our study, few researchers [16][17][18][19] reported early macular thickening in diabetic eyes, however, the difference was not statistically significant. In certain patients they observed significantly higher macular thickness in diabetics without clinical retinopathy when compared with controls.…”

Section: Discussioncontrasting

confidence: 53%

Central Macular Thickness in Diabetic Retinopathy- A Comparative Study

Abrar¹,

Rastogi²,

Ansari³

2017

AIMDR

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Background: Macular oedema is one of the important signs in patients with diabetic retinopathy which progresses to complete blindness. Therefore, early diagnosis of the disease can prevent the progression of disease. Methods: This comparative study was conducted on 200 eyes of 100 diabetics and non-diabetics each. Subjects were divided into five groups according to the International Clinical Diabetic Retinopathy Disease Severity Scale. In each stage, macula was assessed for the presence or absence of Clinically Significant Macular Oedema (CSME) by using Optical Coherence Tomography (OCT) method. Results: The maximum percent of patients are present in the age group of 50-60 years. The maximum and minimum percent of patients in both the genders are diagnosed in the stage 3 and stage 4 retinopathy respectively. The mean Central Macular Thickness (CMT) in the study group was 291.0±63.0 microns and the mean CMT in the control group was 216.5±11.7 microns. Central macular thickness was seen to increase progressively with increasing stages of diabetic retinopathy. A statistically significant difference in mean CMT of controls when compared with each of the diabetic subgroups independently was observed. Conclusion: Macular thickening increased with increasing stages of diabetic retinopathy without evidence of any clinically significant macular oedema. It can be used as a good indicator to monitor such diabetic individuals.

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Section: Discussioncontrasting

confidence: 53%

Central Macular Thickness in Diabetic Retinopathy- A Comparative Study

Abrar¹,

Rastogi²,

Ansari³

2017

AIMDR

View full text Add to dashboard Cite

show abstract

“…Poor glycemic control, longer diabetes duration, hypertension, insulin therapy and body mass index >30 appear to be risk factors [60,61]. Diabetic nephropathy tends to increase the progression of diabetic retinopathy [62]. It is characterized by increased vascular permeability leading to edema and capillary closure resulting in ischemia and neovascularization.…”

Section: Diabetic Retinopathymentioning

confidence: 99%

“…Timely intervention in most cases will prevent complications that threaten vision. The success of laser photocoagulation in treating diabetic retinopathy is well established and vitrectomy plays a vital role in the management of severe complications [62]. Hemodialysis and chronic renal failure do not appear to negatively affect the outcome of laser therapy and vitreoretinal surgery in diabetic patients [74].…”

Section: Special Reportmentioning

confidence: 99%

“…Atherosclerosis is an important risk factor for retinal vascular occlusion [62]. Hypertension is present in up to 64% of young patients with retinal vein occlusion and patients over 50 years of age [62].…”

Section: Retinal Vascular Occlusionmentioning

confidence: 99%

“…Hypertension is present in up to 64% of young patients with retinal vein occlusion and patients over 50 years of age [62]. It usually presents with sudden visual impairment, with the severity being worse in the ischemic type.…”

Section: Retinal Vascular Occlusionmentioning

confidence: 99%

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