RETRACTED ARTICLE: Serum level estimation of some biomarkers in diabetic and non-diabetic COVID-19 infected patients

Khan, Muhammad Usman; Ali, Baida Rihan; Mohammed, Husham Qassim; Al-Shammari, Hayder Mohammed Thyab; Jalil, Abduladheem Turki; Hindi, Nada Khazal Kadhim; Suksatan, Wanich; Saeed, Balsam Qubais; Obaid, Rasha Fadhel; Saleh, Marwan Mahmood; Kadhim, Mustafa M.

doi:10.1007/s13204-021-02167-x

Cited by 12 publications

(5 citation statements)

References 49 publications

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“…According to research, D-dimer values higher than 1 µg/mL increase the risk of death in adult COVID-19 patients with pneumonia. 27,42,43 This parameter was found to be correlated with severe disease progression and mortality. These results suggest that D-dimer could be an early marker of disease progression and a useful tool for guiding treatment in COVID-19 patients.…”

Section: Discussionmentioning

confidence: 95%

“…[23][24][25][26] The clinical state of hospitalized COVID-19 patients is evaluated with the use of generic scoring systems, such as the MEWS. 27 This study was undertaken to determine the presence of correlations between the severity of COVID-19 symptoms based on the MEWS and inflammatory markers. The results confirmed other authors' findings and demonstrated that the concentrations of two inflammatory markers (CRP and IL6) increased with the severity of COVID-19 symptoms classified based on the MEWS.…”

Section: Discussionmentioning

confidence: 99%

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The Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality

Wolszczak-Biedrzycka¹,

Zińczuk²,

Milewska³

et al. 2023

JIR

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Various diagnostic tools are used to assess the severity of COVID-19 symptoms and the risk of mortality, including laboratory tests and scoring indices such as the Modified Early Warning Score (MEWS). The diagnostic value of inflammatory markers for assessing patients with different severity of COVID-19 symptoms according to the MEWS was evaluated in this study. Materials and Methods:The concentrations of CRP (C-reactive protein) (immunoassay) and IL6 (interleukin 6) (electrochemiluminescence assay) were determined, and CRP/IL6, CRP/L, and LCR ratios were calculated in blood serum samples collected from 374 COVID-19 patients. Results: We demonstrated that CRP, IL6, CRP/IL6, CRP/L, LCR inflammatory markers increase significantly with disease progression assessed based on the MEWS in COVID-19 patients and may be used to differentiating patients with severe and non-severe COVID-19 and to assess the mortality. Conclusion:The diagnostic value of inflammatory markers for assessing the risk of mortality and differentiating between patients with mild and severe COVID-19 was confirmed.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

The Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality

Wolszczak-Biedrzycka¹,

Zińczuk²,

Milewska³

et al. 2023

JIR

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“…Infections threatening human (Hesaraki et al, 2021), animal, and even plant health (Lu et al, 2021; Yu et al, 2021) such as COVID 19 (Khan et al, 2022; Widjaja et al, 2021; Xu, al‐Mualm, et al, 2022) are on the rise in all countries of the world (Baghizadeh Fini et al, 2020; Kausikan et al, 2022; Saleh et al, 2020; Singha et al, 2021; Zha et al, 2021). Antibiotics are chemical drug compounds that have been used successfully to kill infections.…”

Section: Introductionmentioning

confidence: 99%

Plant‐mediated synthesis of silver‐doped zinc oxide nanoparticles and evaluation of their antimicrobial activity against bacteria cause tooth decay

Mortezagholi

Movahed

Fathi

et al. 2022

Microscopy Res & Technique

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In this research, silver-doped zinc oxide (SdZnO) nanoparticles (NPs) were synthesized in an environmental-friendly manner. The synthesized NPs were identified by UV-vis spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM). Finally, the antimicrobial activity of synthesized ZnO and SdZnO NPs was performed. It was observed that by doping silver, the size of ZnO NPs was changed. By adding silver to ZnO NPs, the antimicrobial effect of ZnO NPs was improved. Antibacterial test against gram-positive bacterium Streptococcus mutants showed that SdZnO NPs with a low density of silver had higher antibacterial activity than ZnO NPs; Therefore, SdZnO NPs can be used as a new antibacterial agent in medical applications.

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“…Also, new technologies have recently been developed to treat infection [83,[107][108][109][110][111] and cancerous tumours [112][113][114].…”

Section: Introductionmentioning

confidence: 99%

“…These particles can bind to cancer cells through a molecular coating and destroy the cancer cells. Also, new technologies have recently been developed to treat infection [ 83 , 107 , 108 , 109 , 110 , 111 ] and cancerous tumours [ 112 , 113 , 114 ].…”

Section: Introductionmentioning

confidence: 99%

Biosynthesis of silver nanoparticles using Lawsonia inermis and their biomedical application

Alhomaidi

Jasim

Amin

et al. 2022

IET Nanobiotechnology

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Developing biosynthesis of silver nanoparticles (Ag-NPs) using plant extract is an environmentally friendly method to reduce the use of harmful chemical substances. The green synthesis of Ag-NPs by Lawsonia inermis extract and its cellular toxicity and the antimicrobial effect was studied. The physical and chemical properties of synthesised Ag-NPs were investigated using UV-visible spectroscopy, infrared spectroscopy, X-ray diffraction (XRD), scanning, and transmission electron microscopy. The average size of Ag-NPs was 40 nm. The XRD result shows peaks at 2θ = 38.07°, 44.26°, 64.43°, and 77.35°are related to the FCC structure of Ag-NPs. Cytotoxicity of synthesised nanoparticles was evaluated by MTT toxicity test on breast cancer MCF7 cell line. Observations showed that the effect of cytotoxicity of nanoparticles on the studied cell line depended on concentration and time. The obtained IC 50 was considered for cells at a dose of 250 μg/ml. Growth and survival rates decreased exponentially with the dose. Antimicrobial properties of Ag-NPs synthesised with extract were investigated against Escherichia coli, Salmonella typhimurium, Bacillus cereus, and Staphylococcus aureus to calculate the minimum inhibitory concentration and the minimum bactericidal concentration of (MBC). The results showed that the synthesised Ag-NPs and the plant extract have antimicrobial properties. The lowest concentration of Ag-NPs that can inhibit the growth of bacterial strains was 25 μg/ml.

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RETRACTED ARTICLE: Serum level estimation of some biomarkers in diabetic and non-diabetic COVID-19 infected patients

Cited by 12 publications

References 49 publications

The Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality

The Diagnostic Value of Inflammatory Markers (CRP, IL6, CRP/IL6, CRP/L, LCR) for Assessing the Severity of COVID-19 Symptoms Based on the MEWS and Predicting the Risk of Mortality

Plant‐mediated synthesis of silver‐doped zinc oxide nanoparticles and evaluation of their antimicrobial activity against bacteria cause tooth decay

Biosynthesis of silver nanoparticles using Lawsonia inermis and their biomedical application

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