1993
DOI: 10.1016/s0002-9394(14)74450-2
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Retrocorneal Fibrous Membranes in Failed Corneal Grafts

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Cited by 27 publications
(26 citation statements)
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“…20 Due to its continued appositional growth with age, 20 the posterior nonbanded (postnatal) layer provides a lifelong record of pathological events and endothelial function. 24 It may be, therefore, reasonably assumed that the presence of an abnormal retrocorneal PCL reflects rather late intraoperative or postoperative trauma, whereas the presence of abnormal collagen inclusions within Descemet membrane proper indicates an earlier endothelial dysfunction of the donor cornea. In various pathological conditions, including pseudophakic bullous keratopathy after surgical trauma, a fibrous PCL mainly consisting of collagen types IV and VIII and fibronectin, is produced and deposited on the posterior surface of Descemet membrane.…”
Section: Discussionmentioning
confidence: 99%
“…20 Due to its continued appositional growth with age, 20 the posterior nonbanded (postnatal) layer provides a lifelong record of pathological events and endothelial function. 24 It may be, therefore, reasonably assumed that the presence of an abnormal retrocorneal PCL reflects rather late intraoperative or postoperative trauma, whereas the presence of abnormal collagen inclusions within Descemet membrane proper indicates an earlier endothelial dysfunction of the donor cornea. In various pathological conditions, including pseudophakic bullous keratopathy after surgical trauma, a fibrous PCL mainly consisting of collagen types IV and VIII and fibronectin, is produced and deposited on the posterior surface of Descemet membrane.…”
Section: Discussionmentioning
confidence: 99%
“…The incidence of RCM formation is known to be between 0%-7% after a perforating injury of the cornea and up to 54% after failed perforating keratoplasty (11). Risk factors that have been identified for RCM formation include chemical trauma, perforating injury, surgical trauma, and infectious disease.…”
Section: Discussionmentioning
confidence: 99%
“…[1][2][3][4] Retrocorneal membranes arise from (1) epithelial downgrowth (ingrowth), (2) fibroblastic or stromal (keratocytic) downgrowth, (3) fibrous metaplasia of the corneal endothelium, or (4) a combination thereof. 2,3,5 Here, we report, to our knowledge for the first time, the clinicopathologic features and management options of a retrocorneal membrane after Baerveldt shunt implantation for iridocorneal endothelial (ICE) syndrome.…”
Section: Purposementioning
confidence: 99%