Reusable Nanocatalyst: Zirconia and Sulfated Zirconia

Abstract

ABSTRACT1,5-benzodiazepines have been synthesized by Nano Zirconia and Nano Sulfated Zirconia in solvent free conditions. Synthesis was carried out by conventional as well as microwave method. Benzodiazepines were synthesized by reacting o-phenylenediamine and few ketones in the presence of catalytic amount of Nanoparticles. Particles used were sized in between 53-100 nm. Nanoparticles were characterized by FT-IR, DLS and powder XRD analysis.

Reusable Nano-Zirconia-Catalyzed Synthesis of Benzimidazoles and Their Antibacterial and Antifungal Activities

“…Zirconia (ZrO 2 ) NPs are one of the major nanomaterials used for manufacturing refractories, foundry sands, and ceramics. Owing to the desirable mechanical strength, this material is also used in the biomedical field, including biosensors, cancer therapy, implants, joint endoprostheses, and dentistry [ 11 ]. However, the wide application of particles has raised concerns about their potential risks to health and the atmosphere, of which ensuring occupational and consumer safety is an essential concern.…”

“…Thus far, toxicological studies on ZrO 2 NPs are limited, and the results were controversial. Zirconia (ZrO2) is widely used as a ceramic material and has significant applications in catalysts as well [ 11 , 12 ]. Due to its unique chemical properties (i.e., surface acidity and basicity), it is a valuable catalyst for elimination, dehydration, hydrogenation, and oxidation in chemical transformations.…”