Review on hyperemesis gravidarum

Ismail, Siti Khadijah; Kenny, Louise C.

doi:10.1016/j.bpg.2007.05.008

Cited by 107 publications

(107 citation statements)

References 43 publications

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“…It is usually indicative of severe vomiting with dehydration and dyselectrolytemia necessitating hospitalisation in a proportion of patients. 86 It is a disorder typically of the 1st trimester and usually resolves spontaneously by 16 weeks. 87 The exact pathogenesis remains unclear, but several factors may play a role in its causation.…”

Section: Hyperemesis Gravidarum (Hg)mentioning

confidence: 99%

“…[88][89][90] It is more common with molar pregnancy, multiple gestation and especially if the previous pregnancy was complicated by hyperemesis. 86 Diagnosis of HG is that of exclusion and evaluation for other causes is warranted in atypical cases and especially if the vomiting begins or persists into the 2nd trimester. Liver dysfunction, mainly mild-moderate elevation of serum aminotransferases with jaundice only in a minority, is noted in 15-50% of these patients.…”

Section: Hyperemesis Gravidarum (Hg)mentioning

confidence: 99%

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Pregnancy-Related Liver Disorders

Goel

Jamwal

Ramachandran

et al. 2014

Journal of Clinical and Experimental Hepatology

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Pregnancy-related liver disorders accounted for 8% of all maternal deaths at our center from 1999 to 2011. Of the three pregnancy-related liver disorders (acute fatty liver of pregnancy (AFLP), HELLP (Hemolysis, elevated liver enzymes, low platelets) syndrome and pre-eclamptic liver dysfunction, which can lead to adverse maternal and fetal outcome, AFLP is most typically under -diagnosed. Risk of maternal death can be minimised by timely recognition and early/aggressive multi-specialty management of these conditions. Urgent termination of pregnancy remains the cornerstone of therapy for some of these life threatening disorders, but recent advancements in our understanding help us in better overall management of these patients. This review focuses on various aspects of pregnancy-related liver disorders. ( J CLIN EXP HEPATOL 2014;4:151-162) A ny liver disorder can occur co-incidentally in pregnancy. Pregnancy can also occur in a patient with pre-existent chronic liver disorder/portal hypertension. In addition, liver dysfunction in pregnancy can also be secondary to pregnancy (i.e. pregnancy-related liver disorders). The 5 pregnancy-related liver disorders-acute fatty liver of pregnancy (AFLP), HELLP syndrome (hemolysis, elevated liver enzymes and low platelets), pre-eclamptic liver dysfunction, intrahepatic cholestasis of pregnancy (ICP) and hyperemesis gravidarum-occur in different gestational time periods.

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Section: Hyperemesis Gravidarum (Hg)mentioning

confidence: 99%

Section: Hyperemesis Gravidarum (Hg)mentioning

confidence: 99%

Pregnancy-Related Liver Disorders

Goel

Jamwal

Ramachandran

et al. 2014

Journal of Clinical and Experimental Hepatology

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“…In general, HEG occurs in the first trimester of pregnancy, but it can be seen as late as the twentieth week. Due to life-threatening complications such as weight loss, ketonuria, and electrolyte imbalance, it often requires hospitalization [2].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the hematologic system as a marker of subclinical inflammation in hyperemesis gravidarum: a case control study

et al. 2017

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Objectives: Current evidence suggests that subclinical inflammation plays a significant role in the development of hyperemesis gravidarum (HEG). Simple hematological markers, such as mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR), have been shown to reflect inflammatory burden and disease activity in several disorders. This study aimed to determine the diagnostic value of these hematological parameters for HEG. Material and methods:A total of 54 HEG patients and 58 age-and gestational-age-matched control subjects were studied. NLR, MPV, PLR, platelet distribution width (PDW), and red cell distribution width (RDW) values in all patients were calculated and recorded from complete blood cell counts.Results: For HEG patients, the median NLR was 3.2 (1.6-7.1), and the median PLR was 143.7 (78.1-334.6); for control subjects, the values were 2.1 (1.0-4.7) and 93.1 (47.3-194.7), respectively. Although both the NLR and PLR of HEG patients were found to be significantly higher than in the controls, no significant difference was found between the study groups in terms of MPV, RDW, or PDW. Correlation analysis revealed a significant correlation between NLR and CRP (r = 0.872, p < 0.001). Conclusions:Our results show that peripheral blood NLR and PLR values can reflect inflammatory burden in HEG patients and can be used as markers for HEG.

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“…N ausea and vomiting are common problems during pregnancy; 70-85% of pregnant women experience nausea and vomiting in the first half of pregnancy (1). Hyperemesis gravidarum (HG) is a condition with severe nausea and vomiting, which is seen in 0.3-2% of pregnancies.…”

Section: Introductionmentioning

confidence: 99%

Psychiatric symptoms, perceived social support, coping styles, and dyadic adjustment in pregnant women with hyperemesis gravidarum

Kara¹,

Kalem²,

Balci³

et al. 2016

Dusunen Adam

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Psychiatric symptoms, perceived social support, coping styles, and dyadic adjustment in pregnant women with hyperemesis gravidarum Objective: Hyperemesis gravidarum (HG) is a condition with severe nausea and vomiting, which is seen in 0.3-2% of pregnancies. In addition to biological factors, psychosocial factors were also reported to play a role in the development of HG. However, the impact of psychosocial factors in HG has not been elucidated yet. In this research, we aimed to investigate psychiatric symptoms in patients with HG and their relationships with perceived social support, coping styles, and dyadic adjustment. Method: Forty-eight women with HG hospitalized in the Obstetrics and Gynecology Inpatient Unit and 48 healthy pregnant women consulted to the Obstetric Outpatient Unit for their routine obstetric control were recruited for the study. The subjects were evaluated with sociodemographic form, Symptom Check List (SCL-90-R), Multidimensional Scale of Perceived Social Support (MSPSS), Ways of Coping Scale (WCS), and Dyadic Adjustment Scale (DAS). Results: All sociodemographic variables except nausea and vomiting history in previous pregnancies were similar in both groups. All subscales and global symptom index scores of SCL-90-R were higher; optimistic and submissive subscale scores of WCS were lower, satisfaction, consensus and total scores of DAS were higher in HG group (p<0.05). Conclusion: Psychiatric symptom levels are higher in women with HG compared to the controls. No difference for previous psychiatric history among groups shows that previous psychiatric history is not a predictor for HG. The psychiatric symptoms in HG is self-limiting and possibly due to HG symptoms. Psychosocial factors such as perceived social support, coping styles, and dyadic adjustment may contribute to the psychiatric symptoms. Keywords: Coping styles, dyadic adjustment, hyperemesis gravidarum, perceived social support, psychiatric symptoms ÖZET Hiperemezis gravidarumu olan gebelerde ruhsal belirtiler, stresle başa çıkma tarzları, algılanan sosyal destek ve çift uyumu Amaç: Hiperemezis gravidarum (HG), şiddetli bulantı-kusma ile giden ve gebelerin yaklaşık %0.3-2'sinde görülen bir tablodur. Biyolojik etkenler yanında psikososyal etkenlerin de HG gelişiminde rol oynayabileceği bildirilmiştir. Fakat, HG'de psikososyal etkenlerin rolü tam olarak gösterilememiştir. Bu çalışmada HG ile ruhsal belirtiler ve bu belirtilerin algılanan sosyal destek, stresle başa çıkma tarzları ve çift uyumu arasındaki ilişkisini değerlendirmeyi hedefledik. Yöntem: Kadın Hastalıkları ve Doğum Kliniği'nde HG tanısı ile yatırılan 48 gebe ile hastanenin Kadın Hastalıkları ve Doğum polikliniğine rutin doğum öncesi kontroller için başvuran 48 sağlıklı gebe çalışmaya alındı. Denekler, sosyodemografik form, Belirti Tarama Listesi (SCL-90-R), Çok Boyutlu Algılanan Sosyal Destek Ölçeği (ÇBASDÖ), Stresle Başaçıkma Tarzları Ölçeği (SBTÖ) ve Çift Uyum Ölçeği (ÇUÖ) ile değerlendirildi. Bulgular: Bulantı kusma öyküsü dışında tüm sosyodemografik değişk...

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Review on hyperemesis gravidarum

Cited by 107 publications

References 43 publications

Pregnancy-Related Liver Disorders

Pregnancy-Related Liver Disorders

Evaluation of the hematologic system as a marker of subclinical inflammation in hyperemesis gravidarum: a case control study

Psychiatric symptoms, perceived social support, coping styles, and dyadic adjustment in pregnant women with hyperemesis gravidarum

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