Review on leptin and adiponectin responses and adaptations to acute and chronic exercise

Bouassida, Anissa; Chamari, Karim; Zaouali, Monia; Feki, Youssef; Zbidi, Abdelkarim; Tabka, Zouhaïr

doi:10.1136/bjsm.2008.046151

Cited by 255 publications

(264 citation statements)

References 93 publications

(116 reference statements)

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“…Accordingly, it is reasonable to speculate that the reduction in body fat mass led to decreased expression of leptin and improvement in leptin resistance. Our results are in accordance with previous studies which showed that exercise programs resulting in reduced fat mass usually decreased leptin concentration (Bouassida et al, 2010).…”

Section: Discussionsupporting

confidence: 94%

Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: A randomized controlled trial

Huang

Larsen

Møller

et al. 2015

Preventive Medicine

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This file was dowloaded from the institutional repository Brage NIH -brage.bibsys.no/nih Huang, T., Larsen, K. T., Møller, N. C., Ried-Larsen, M., Frandsen, U., Andersen, L. B. (2015 Methods:One hundred and fifteen children were recruited in Odense, Denmark (2011Denmark ( -2014. The participants were randomly allocated to either the day camp intervention arm (DCIA) or the standard intervention arm (SIA). The intervention for the DCIA comprised a 6-week camp intervention and a 46-week family-based intervention. The SIA was offered one weekly physical activity session for 6 weeks and one educational meeting. C-reactive protein (CRP), monocyte chemoattractant protein-1 (MCP1), leptin, and adiponectin were measured in serum at baseline, 6 weeks and 52 weeks.Results: Compared with the SIA, the reductions in CRP (P=0.003) and leptin (p<0.001) were larger in the DCIA at 6 weeks. The intervention effects on leptin were significantly mediated by the changes in body fat mass. No intervention effects on CRP and leptin were seen at 52 weeks. No between-group differences in changes in MCP1 and adiponectin were observed at 6 weeks or 52 weeks. Conclusions:The 6-week camp intervention resulted in reductions in CRP and leptin. The intervention effects did not persist to 52 weeks. The intervention effect on leptin was explained by the changes in body fat mass.

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Section: Discussionsupporting

confidence: 94%

Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: A randomized controlled trial

Huang

Larsen

Møller

et al. 2015

Preventive Medicine

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“…One explanation for these findings is thought to be because of beneficial effects of physical activity (PA) on endothelial function and the relatively less well‐studied biomarkers of atherosclerosis 5, 6, 7, 8, 9, 10, 11, 12. The anti‐inflammatory effects of PA have been well documented with consistent findings of decreases in pro‐inflammatory markers C‐reactive protein (CRP) and interleukin‐6 (IL‐6) following brief exercise interventions,8, 9 in addition to decreases in leptin and increases in adiponectin levels with exercise‐induced fat loss 5. PA also improves endothelial function in terms of its ability to release the protein tissue‐plasminogen activator (t‐PA), but the influence of PA on the cell adhesion molecule E‐selectin is uncertain 6.…”

Section: Introductionmentioning

confidence: 99%

Physical Activity, Sedentary Time, and Cardiovascular Disease Biomarkers at Age 60 to 64 Years

Elhakeem

Cooper

Whincup

et al. 2018

JAHA

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BackgroundWe examined associations of objectively measured physical activity (PA) and sedentary time with cardiovascular disease biomarkers at age 60 to 64 years. This included investigation of sex differences and the extent to which associations may be mediated by adiposity.Methods and ResultsParticipants were 795 men and 827 women aged 60 to 64 years from the Medical Research Council National Survey of Health and Development. Combined heart rate and movement sensors worn for 5 consecutive days were used to derive overall PA energy expenditure, kJ/kg per day) and time spent sedentary (<1.5 metabolic equivalent of tasks), in light PA (1.5–3 metabolic equivalent of tasks) and moderate‐to‐vigorous intensity PA (>3 metabolic equivalent of tasks). Linear regression models were used to relate each PA parameter to inflammatory (C‐reactive protein, interleukin‐6), endothelial (tissue‐plasminogen activator, E‐selectin) and adipokine (leptin, adiponectin) markers extracted from fasting blood samples. Greater time in light PA and moderate‐to‐vigorous intensity PA and less sedentary time were associated with more favorable biomarker levels. For C‐reactive protein, interleukin‐6, and leptin, these differences were greater among women than men. For example, % differences (95% confidence intervals) in leptin for men and women per SD increases in sedentary time: 7.9 (2.7, 13.0) and 20.6 (15.3, 25.8); moderate‐to‐vigorous intensity PA: −3.8 (−8.9, 12.7) and −17.7 (−23.1, −12.4), moderate‐to‐vigorous intensity PA: −12.9 (−17.9, −8.0) and −18.3 (−23.4, −13.1). Fat mass mediated a greater proportion of these associations in women than men.ConclusionsGreater light PA and moderate‐to‐vigorous intensity PA and less sedentary time in early old age were associated with more favorable cardiovascular biomarker profiles. Fat mass partially mediated these associations but more strongly in women than men, which explained sex differences.

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“…Bouassida et al (20) argued that leptin reduction occurs after the physical activities in which the energy consumption is higher than 800 kcal. Therefore, the higher energy consumption during intermittent exercise might be one possible cause of leptin reduction; as such reduction did not occur after the continuous exercise in this study.…”

Section: Discussionmentioning

confidence: 99%

The Effects of 3000 Meters Swimming on Serum Level of Leptin and Glucose Under 2 Different Intensities: Continuous and Intermittent

Fard¹,

Shakerian²,

Habibi³

et al. 2015

Jentashapir J Health Res

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Background: Leptin, that is a marker of fat mass in the body, has an important role in the body total metabolism and glucose homeostasis. Objectives: This study sought to determine whether subjects' plasma leptin and glucose level were affected by the type of intensity exercise they carried out. Materials and Methods: A total of 24 male elite swimmers (Mean age: 25.33, SD: 3.54 y) were randomly assigned into one of two groups: control and training. Study design consisted of pretest, training phase, and the posttest phase (immediately and 24 hours after training). Participants of the training group took part in two training conditions: continuous and intermittent. Serum leptin and glucose were measured in pretest and posttest phases. Results:The results demonstrated that serum leptin and glucose were significantly decreased in intermittent exercise compared to continuous intensity exercise. Furthermore, zero-order correlation indicated significant relationship between serum leptin and glucose in the posttest of intermittent type of intensity exercise. Conclusions: Overall, the results of this study indicate that intermittent exercise reduces the plasma leptin level. In addition, this reduction is significantly correlated to the glucose level in the blood. The continuous exercise was shown to have no effects on the plasma leptin level, and there was no relationship between the glucose and leptin levels.

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Review on leptin and adiponectin responses and adaptations to acute and chronic exercise

Cited by 255 publications

References 93 publications

Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: A randomized controlled trial

Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: A randomized controlled trial

Physical Activity, Sedentary Time, and Cardiovascular Disease Biomarkers at Age 60 to 64 Years

The Effects of 3000 Meters Swimming on Serum Level of Leptin and Glucose Under 2 Different Intensities: Continuous and Intermittent

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