Rhodiola rosea: main features and its beneficial properties

Durazzo, Alessandra; Lucarini, Massimo; Nazhand, Amirhossein; Coêlho, Angélica Gomes; Souto, Eliana B.; Arcanjo, Daniel Dias Rufino; Santini, Antonello

doi:10.1007/s12210-022-01055-y

Cited by 5 publications

(2 citation statements)

References 59 publications

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“…Citations per publication are represented by the color of the bubble (citations per publication, CPP). This quantitative research analysis approach was carried out in previous researches on natural products [20][21][22].…”

Section: Griffonia Simplicifolia: Quantitative Research Literature An...mentioning

confidence: 99%

Beneficial Properties and Sustainable Use of a Traditional Medicinal Plant: Griffonia simplicifolia

Nazhand,

Durazzo,

Lucarini

et al. 2024

Challenges

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Since ancient times, medicinal plants have been a universal source of biologically active substances with high potential for the treatment of various diseases and disorders. For centuries, traditional communities have often relied on medicinal plants to treat health problems. Therefore, accurate information is required and knowledge about traditional medicinal plants requires evaluation, and great attention should be given to the possible integration of these plants as therapeutic agents or as complements to conventional pharmacological therapies in the healthcare system. Recently, Griffonia simplicifolia (DC.) Baill., initially used as a holistic remedy, has attracted attention from many researchers and consumers because of its multiple health-promoting effects. This growing interest prompted us to give an updated review of the botanical, geographical, historical, and therapeutic potentials of Griffonia simplicifolia (DC.) Baill. in terms of its in vitro and in vivo health effects, nutritional uses, and possible applications in line with biodiversity and sustainability concepts. This paper also presents a quantitative research analysis of the published studies related to this plant that are available in the literature. To retrieve the publications related to this plant, a bibliographic search was carried out using the Scopus database. The bibliometric data were extracted and processed using VOSviewer software (v.1.6.16, 2020). Technological possible applications in terms of patents request presented was also performed. A total of 1386 publications, from the year 1970 to the year 2021, were obtained by the literature search, and these had been collectively cited 38,805 times. The large amount of literature data available documents the interest in this plant’s use as a tool for integrating traditional holistic healing approach, e.g., using plants, herbs, and holistic remedies, into the healthcare system as supporting tools and/or therapeutic agents, which is a current worldwide challenge.

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Section: Griffonia Simplicifolia: Quantitative Research Literature An...mentioning

confidence: 99%

Beneficial Properties and Sustainable Use of a Traditional Medicinal Plant: Griffonia simplicifolia

Nazhand,

Durazzo,

Lucarini

et al. 2024

Challenges

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“…The United States Pharmacopeia allows 0.3% rosavins and 0.08% salidroside [6]; according to the Russia State Pharmacopoeia, the rosavin content must be not less than 1% and not less than 0.8% in terms of salidroside [7]; the Australian standard for the extract is not less than 1.8% phenylpropanoids, 1.2% rosavin, and 0.6% salidroside (https://www.tga.gov.au/ resources/resource/compositional-guidelines/dried-root-powdered-rhodiola-rosea; accessed on 2 June 2023). Pharmacological studies on R. rosea are numerous [1,[8][9][10][11][12][13][14][15]. Adaptogenic properties of R. rosea are mostly related to the presence of these marker compounds [16], while antioxidant activity is mainly due to organic acids and flavonoids [17].…”

Section: Introductionmentioning

confidence: 99%

Individual Differences in Growth and in Accumulation of Secondary Metabolites in Rhodiola rosea Cultivated in Western Siberia

Эрст

Kotsupiy

Erst

et al. 2023

IJMS

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In this study, growth parameters of underground parts and concentrations of phenylpropanoids, phenylethanoids, flavonoids, hydroxybenzoic acids, and catechins in aqueous–ethanol extracts of 6-year-old cultivated plants of Rhodiola rosea (propagated in vitro) of Altai Mountain origin were analyzed, and differences in chemical composition among plant specimens and between plant parts (rhizome and root) were evaluated. High-performance liquid chromatography detected 13 phenolic compounds. Roots contained 1.28 times higher phenylethanoids levels (1273.72 mg/100 g) than rhizomes did. Overall, the concentration of phenylethanoids in underground organs was not high and ranged from 21.36 to 103.00 mg/100 g. High variation among R. rosea individual plants was noted both in growth characteristics and in levels of secondary metabolites under our cultivation conditions. It was found that concentrations of phenylpropanoids, phenylethanoids, and catechins significantly depend on the plant part analyzed (p ≤ 0.05). Specimen No. 4 is characterized by the highest concentration of rosavins (1230.99 mg/plant) and the lowest concentration of cinnamyl alcohol (62.87 mg/plant). Despite the wide range of values, all 10 tested specimens (underground part) met the minimum requirements of the United States Pharmacopeia (2015) for rosavins (0.3%) and of the Russia State Pharmacopoeia (2015) for the average level of rosavins (roots): (1%).

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