Ribosomal proteins cross-linked to peptide chain termination release factor 2.

Translational termination: "stop" for protein synthesis or "pause" for regulation of gene expression

“…This suggests that the RF might interact directly with the peptidyltransferase domain to influence its conformation (Tate et al, 1983b). Moreover, L2, mapped within the center (and still a putative candidate for a peptidyltransferase enzyme), can be cross-linked to RF-2 (Stoffler et al, 1982;Lang et al, 1989). A summary of the ribosomal determinants, their spacial orientation within the two subunits of the 70S ribosome (presented as a view from the top of the ribosome), and their relationships with the release factor are shown in Figure 3B.…”