Risk assessment of streptomycin and tetracycline residues in meat and milk on Croatian market

Vragović, Natalija; Bažulić, Davorin; Njari, Bela

doi:10.1016/j.fct.2010.11.006

Cited by 97 publications

(47 citation statements)

References 18 publications

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“…Also, the ADI value of ENR was used for the assessment of NOR in the present study. Based on the estimated daily intake and comparison with the acceptable daily intake, the risk was assessed as negligible when the ''level of achievement'' was less than 1% of the ADI (\1% of ADI), as considerably if the ''level of achievement'' was 1-5% of the ADI (1-5% ADI) and as distinctively if the ''level of achievement'' was greater than 5% of the ADI ([5% of ADI) (Vragović et al 2011). From the results shown in Table 4, the EDI values of FQs via the average consumption of marine fish were far below the ADI recommendation, indicating that this intake amount would not pose a human health risk in Guangdong Province, China, at present.…”

Section: Risk Assessment To Human Healthmentioning

confidence: 99%

Residues of fluoroquinolones in marine aquaculture environment of the Pearl River Delta, South China

Wang

Nie

et al. 2011

Environ Geochem Health

118

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Concentrations and distributions of selected fluoroquinolones (norfloxacin, ciprofloxacin and enrofloxacin) in water, sediments and nine kinds of fish species collected from 6 sites in two marine aquaculture regions of the Pearl River Delta, China, were analyzed by using high-performance liquid chromatography with fluorescence detector (HPLC). The results showed that the concentrations of ciprofloxacin and enrofloxacin were below the limits of quantification (LOQ) in all water samples except for norfloxacin. Norfloxacin and ciprofloxacin concentrations ranged from 1.88 to 11.20 ng g(-1) dry wt, 0.76-2.42 ng g(-1) dry wt in sediments collected from the Dapeng'ao region (sites 1-3) and ranged from 2.31 to 4.75 ng g(-1) dry wt, 1.26-1.76 ng g(-1) dry wt in sediments collected from the Hailing Island region (sites 4-6), respectively. However, no enrofloxacin was found in all sediment samples. The three fluoroquinolones (FQs) were detected in all fish samples, and the concentrations were higher in liver tissues than those in muscle tissues. The levels of norfloxacin were higher than ciprofloxacin and enrofloxacin in both liver and muscle tissues. Among the nine marine fish species, Siganus fuscescens from Hailing Island had a significantly high level of norfloxacin in liver tissue (254.58 ng g(-1) wet wt), followed by Sparus macrocephalus (133.15 ng g(-1) wet wt) from Dapeng'ao, and the lowest value was Lutianus argentimaculatus (5.18 ng g(-1) wet wt) from Hailing Island. The obtained results of FQs in present study do not represent a risk to the human health in Guangdong coastal area, based on the maximum residue limits (MRLs) established by Chinese Government and the acceptable daily intake (ADI) recommended by the Food and Agriculture Organization and World Health Organization (FAO/WHO).

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Section: Risk Assessment To Human Healthmentioning

confidence: 99%

Residues of fluoroquinolones in marine aquaculture environment of the Pearl River Delta, South China

Wang

Nie

et al. 2011

Environ Geochem Health

118

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“…Kontaminasi residu juga sering terjadi di luar negeri diantaranya hasil survei di Nigeria ditemukan residu obat hewan dalam jaringan ayam yaitu 59 dari 178 broiler (33,1%) dan oksitetrasiklin merupakan obat yang paling banyak digunakan. Studi di Kroasia, rata-rata kadar streptomycin dalam daging 44,14 μg/kg dan dalam susu 15,57 μg/kg, kadar tetrasiklin dalam daging 1,62 μg/kg dan dalam susu 1,5 μg/kg (Kabir et al, 2004;Vragovic et al, 2011). Donkor et al (2011) melaporkan bahwa prevalensi residu obat hewan di Ghana sebanyak 21,1% dalam sampel produk asal hewan.…”

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Pengaruh pemberian antibiotika saat budidaya terhadap keberadaan residu pada daging dan hati ayam pedaging dari peternakan rakyat

Zubaidah

Sutrisno

2015

JIIP

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:The use of antibiotics in animal husbandry cannot be avoided either as an act of therapy, supportive or prevention. This study was aimed to determine the existence of antibiotic residues in broiler chicken products which were produced by poultry farm and to determine the safety level of residues in the product which was associated with a drug application and harvesting time. Thigh meat and liver samples of broiler were taken when thinning and harvesting time in poultry farm at Pamijahan-Bogor using purposive sampling method. Residue testing was conducted through bioassay screening test. Positive results were followed by a confirmatory test using HPLC. Total positive samples were detected residues reached 27.08% which included the macrolide group reached 22.92% and tetracycline group reached 4.17%. These residues were found in the liver, reaching 50% of the total sample of the liver. In addition, 53.85% of the positive samples came from broiler chicken samples taken during thinning period. Macrolide antibiotics in liver samples were detected in the form of erythromycin with the level compounds between 0085 -0702 ppm. Moreover, 90.9% of the samples had levels exceeding MRL defined in SNI 01-6366-2000 and CAC/MRL-2-2012. Tetracycline antibiotic was detected in the form of doxycycline with the level compounds between 0-0067 ppm on thigh meat and 0-0085 ppm in the liver although these levels were still below the MRL. The residues existence was closely related to the drug dose and farmer's knowledge about withdrawal time.

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“…The European Regulation No. 178/2002/EU (European Commission, 2002 states that in EU the food business operators have the primary legal responsibility for ensuring food safety, and it is generally recognised that producers are in the best position to devise methods for warranting the food safety (Vragović et al, 2011). In dairy plants, it may be difficult to implement a control programme to avoid residues of veterinary antimicrobials in milk due to the large number of different compounds and formulations commercially available.…”

Section: Introductionmentioning

confidence: 99%

Survey on Antimicrobial Residues in Raw Milk and Antimicrobial Use in Dairy Farms in the Emilia-Romagna Region, Italy

Serraino

Giacometti

Marchetti

et al. 2013

Italian Journal of Animal Science

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This survey investigated the antimicrobials most commonly used in dairy herds and antimicrobial residues most frequently detected in milk to evaluate the suitability of rapid screening tests to determine antimicrobial residues in milk. The investigation was carried out in 45 dairy herds consulting the farm administration records and in a national dairy industry collecting milk from almost all the dairy farms studied. Data were recorded on: i)

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Risk assessment of streptomycin and tetracycline residues in meat and milk on Croatian market

Cited by 97 publications

References 18 publications

Residues of fluoroquinolones in marine aquaculture environment of the Pearl River Delta, South China

Residues of fluoroquinolones in marine aquaculture environment of the Pearl River Delta, South China

Pengaruh pemberian antibiotika saat budidaya terhadap keberadaan residu pada daging dan hati ayam pedaging dari peternakan rakyat

Survey on Antimicrobial Residues in Raw Milk and Antimicrobial Use in Dairy Farms in the Emilia-Romagna Region, Italy

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