2012
DOI: 10.12669/pjms.291.2828
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Risk factors for coronary heart disease in patients below 45 years of age

Abstract: Objective: To examine the traditional risk factors and biochemical profile of patients with established CAD (coronary artery disease), and compare the trends of these in specified age groups of different populations as depicted in various studies. Methodology: All consecutive patients below 45 years of age, having classical history of Ischemic heart disease and also having definite ECG changes consistent with coronary artery disease were enrolled. These patients were admitted to CCU/Intermediate Coronary Care … Show more

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Cited by 35 publications
(50 citation statements)
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“…Additionally, positive family history of CAD, smoking, hypertension, increased body mass index (BMI), dyslipidemia and diabetes mellitus (DM) are among the main risk factors of CAD in patients younger than 45 years [9]. There are numerous risk factors for CAD in young adults and a number of atherosclerosis risk factors intensify the severity of coronary atherosclerosis in this population [10].…”
Section: Introductionmentioning
confidence: 99%
“…Additionally, positive family history of CAD, smoking, hypertension, increased body mass index (BMI), dyslipidemia and diabetes mellitus (DM) are among the main risk factors of CAD in patients younger than 45 years [9]. There are numerous risk factors for CAD in young adults and a number of atherosclerosis risk factors intensify the severity of coronary atherosclerosis in this population [10].…”
Section: Introductionmentioning
confidence: 99%
“…The association between EH and GCK polymorphisms was previously disclosed in several studies (21,22). GCK gene-body hypomethylation was associated with the risk of coronary heart disease (23), which is closely correlated with EH (24,25). The present study performed an association study of GCK gene-body methylation with the risk of EH, in order to assess whether GCK methylation is associated with EH, and to examine the interactions between GCK methylation and age, as well as clinical indicators.…”
Section: Introductionmentioning
confidence: 82%
“…Weighted density score for highest attenuation value was graded as: 2 as in study done by Nadeem M. et al [4] Univariate analysis was done to see the relationship between independent variables and outcome variable. The outcome variable was a low (up to 160) or a high (> 160) Agatston score.…”
Section: Methodsmentioning
confidence: 99%