Risks and Management of Sodium Hypochlorite in Endodontics

Mathew, Shibu Thomas

doi:10.4172/2332-0702.1000178

Cited by 18 publications

(38 citation statements)

References 45 publications

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“…5 The amount of the extruded irrigant might be related to applying high pressure on the syringes, wedging the needle and the large size of the apex, which is observed more frequently in immature teeth. 6 Endodontic treatment of immature permanent teeth with necrotic pulp or apical pathosis has always been a challenge, since mechanical instrumentation might result in further weakening of the dentinal walls of the canal, making it more difficult to obtain an apical seal. 7 Currently, there is a shift in treating these teeth toward revascularization, which would allow root development to continue, and according to many case reports, this procedure has proved its success.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the apical extrusion of sodium hypochlorite gel in immature permanent teeth: An in vitro study

Nesser¹,

Bshara²

2019

Dent. Med. Probl.

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Section: Introductionmentioning

confidence: 99%

Evaluation of the apical extrusion of sodium hypochlorite gel in immature permanent teeth: An in vitro study

Nesser¹,

Bshara²

2019

Dent. Med. Probl.

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“…However, it alters the composition of the organic and inorganic structures of the tooth [13,14]. Moreover, it is toxic to the tissues due to its chemical nature [16]. Therefore, various studies evaluating the potential of natural materials for use as root canal irrigation solutions have been conducted [5,6,9,10,17,18].…”

Section: Irrigation Solution Influence To Dentin's Microhardnessmentioning

confidence: 99%

Effect of Grape Seed Extract Solution on the Microhardness of the Root Canal Dentin: An in Vitro Study

Alinda

Margono²,

Asrianti³

2020

Int J App Pharm

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Objective: Grape seed extract (GSE) containing proanthocyanidin as a root canal irrigation solution has its antibacterial effects and ability to eliminatethe smear layer. In addition, proanthocyanidin acts as a cross-linking agent of collagen, which adds to dentin’s mechanical properties. This studyanalyzed the effect of GSE containing 2.9% proanthocyanidin on the microhardness of the dentin in the root canal.Methods: Fifty teeth were divided into three groups and immersed in GSE solution, 3% NaOCl solution, or distilled water (controls) for 30 min for 3consecutive days. The microhardness was measured using the Vickers method. Data were analyzed using the Kruskal–Wallis test.Results: The GSE group presented the highest microhardness values, whereas the lowest values in the NaOCl group. No significant difference inmicrohardness observed between the GSE and distilled water groups.Conclusion: The GSE solution maintains the microhardness of the root canal dentin.

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“…[11] The unpleasant taste, high toxicity, and its inability to remove the smear layer were the main disadvantages of NaOCl. [12][13][14] Furthermore, an increase in antibioticresistant strains and side effects caused by synthetic drugs has provoked researchers toward herbal alternatives.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antimicrobial Efficacy of Herbal Extracts (Tridax procumbens and Aegle Marmelos) and 5% Sodium Hypochlorite as Irrigants against Enterococcus faecalis: An In Vitro Study

2019

IJDA

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Background: Oral microorganisms, which are usually opportunistic pathogens invade a root canal containing necrotic tissue and establish an infectious process causing primary endodontic infections. When root canal remains infected for long periods, the number of facultative anaerobic bacteria increases. The most common facultative anaerobic Gram-positive coccus cultured from non-healing endodontic cases is Enterococcus species. Aims and Objectives: The present study was done to evaluate the antimicrobial efficacy of Tridax procumbens, Aegle marmelos, and 5% sodium hypochlorite against Enterococcus faecalis biofilm formed on the tooth substrate. Materials and Methods: Extracted human teeth were biomechanically prepared, vertically sectioned, placed in the tissue culture wells exposing the root canal surface to E. faecalis to form a biofilm. At the end of the 3 rd and 6 th weeks, all groups were treated for 10 min with the test solutions and control and were analyzed qualitatively and quantitatively. Results: Qualitative assay with 3-week biofilm showed complete inhibition of bacterial growth with T. procumbens, A. marmelos and NaOCl, except saline, which showed the presence of bacterial growth. In quantitative analysis, Aegle and saline-treated tooth samples showed 1.344 ±123 CFU/mL and 186.4 × 10 9 ± 4.1 × 10 9 CFU/mL (mean and standard deviation), respectively. Qualitative assay with 6-week biofilm showed growth when treated with Tridax and marmelos whereas NaOCl has shown complete inhibition. All treated groups have shown a significant reduction of the bacterial population compared with the control group, and NaOCl showed 100% reduction. Conclusion: Nearly 5% sodium hypochlorite showed maximum antibacterial activity against E. faecalis biofilm formed on tooth substrate. T. procumbens, A. marmelos also showed statistically significant antibacterial activity.

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Risks and Management of Sodium Hypochlorite in Endodontics

Cited by 18 publications

References 45 publications

Evaluation of the apical extrusion of sodium hypochlorite gel in immature permanent teeth: An in vitro study

Evaluation of the apical extrusion of sodium hypochlorite gel in immature permanent teeth: An in vitro study

Effect of Grape Seed Extract Solution on the Microhardness of the Root Canal Dentin: An in Vitro Study

Evaluation of Antimicrobial Efficacy of Herbal Extracts (Tridax procumbens and Aegle Marmelos) and 5% Sodium Hypochlorite as Irrigants against Enterococcus faecalis: An In Vitro Study

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