Role of the posterior parietal cortex in updating reaching movements to a visual target

Desmurget, Michel; Epstein, Charles M.; Turner, Robert S.; Prablanc, Claude; Alexander, Garrett E.; Grafton, Scott T.

doi:10.1038/9219

Cited by 728 publications

(504 citation statements)

References 32 publications

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“…A second alternative explanation would suggest that the modulation of the excitability of the CST might be triggered by the output of a conflict monitoring system involving the DLPFC and the ACC (Botvinick et al, 2001). Previous studies administered single or brief burst of high-frequency magnetic pulses to different regions of the brain in specific time intervals respect to an event in order to momentarily disrupt the corresponding neural activity at specific stages of the task (Desmurget et al, 1999;Pascual-Leone et al, 2000;Vesia et al, 2010). Particularly, applying single pulses to these regions at specific time intervals respect to the commission of mistaken responses might help to disentangle i) their functional role by measuring the behavioral effect of the suppression of its activity and (ii)the exact time-course of their activation.…”

Section: Discussionmentioning

confidence: 99%

Tracking post-error adaptation in the motor system by transcranial magnetic stimulation

et al. 2013

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Abstract-The commission of an error triggers cognitive control processes dedicated to error correction and prevention. Post-error adjustments leading to response slowing following an error (''post-error slowing''; PES) might be driven by changes in excitability of the motor regions and the corticospinal tract (CST). The time-course of such excitability modulations of the CST leading to PES is largely unknown. To track these presumed excitability changes after an error, single pulse transcranial magnetic stimulation (TMS) was applied to the motor cortex ipsilateral to the responding hand, while participants were performing an Eriksen flanker task. A robotic arm with a movement compensation system was used to maintain the TMS coil in the correct position during the experiment. Magnetic pulses were delivered over the primary motor cortex ipsilateral to the active hand at different intervals (150, 300, 450 ms) after correct and erroneous responses, and the motor-evoked potentials (MEP) of the first dorsal interosseous muscle (FDI) contralateral to the stimulated hemisphere were recorded. MEP amplitude was increased 450 ms after the error. Two additional experiments showed that this increase was neither associated to the correction of the erroneous responses nor to the characteristics of the motor command. To the extent to which the excitability of the motor cortex ipsi-and contralateral to the response hand are inversely related, these results suggest a decrease in the excitability of the active motor cortex after an erroneous response. This modulation of the activity of the CST serves to prevent further premature and erroneous responses. At a more general level, the study shows the power of the TMS technique for the exploration of the temporal evolution of post-error adjustments within the motor system. Ó

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Section: Discussionmentioning

confidence: 99%

Tracking post-error adaptation in the motor system by transcranial magnetic stimulation

et al. 2013

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“…Desmurget and colleagues have provided a tool to determine behaviorally whether the dorsal stream is critically involved in specific aspects of a task (Desmurget et al, 1999;Pisella et al, 2000). Using transcranial magnetic stimulation and a patient study, they showed that part of the dorsal route (the posterior parietal cortex) is necessary for fast (less than 150-ms latency) corrections of ongoing pointing movements to perturbations of object locations.…”

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confidence: 99%

10 years of illusions.

Smeets

Brenner

2006

Journal of Experimental Psychology: Human Perception and Perfor

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A decade ago, S. Aglioti, J. F. X. DeSouza, and M. A. Goodale (1995) published an experiment that has had a big influence on the way that visual information is thought to control human behavior. Their findings have often been simplified as suggesting that action is immune to perceptual illusions. The current authors critically analyze the 4 steps involved in this simplification and argue that research during the last 10 years has shown that the validity of 3 of the 4 steps is doubtful. They conclude that this experiment cannot be regarded as firm support for the 2-visual-systems hypothesis (i.e., that the ventral stream is for perception and the dorsal stream is for visually guided actions).

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“…This indicates that the right PPC is not critically involved in updating self-location along straight paths. We found this surprising, considering the aggregation of evidence for impaired eye and arm position updating after PPC lesions [15,16,29,65]. Before abandoning the notion that the PPC is a critical structure for updating during locomotion, however, other types of locomotion and more complex trajectories should be tested.…”

Section: Discussionmentioning

confidence: 92%

“…Future testing with left hemisphere patients promises to shed light on this issue. Evidence is scant for lateralization of the neural substrates of arm position updating, but there are reports that lesions to or stimulation of the left PPC can lead to de®cits in updating during reaches [15,65], at least for reaches made by the contralateral arm.…”

Section: Discussionmentioning

confidence: 99%

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Intact spatial updating during locomotion after right posterior parietal lesions

et al. 2000

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One function of the posterior parietal cortex (PPC) is to monitor and integrate sensory signals relating to the current pointing direction of the eyes. We investigated the possibility that the human PPC also contributes to spatial updating during larger-scale behaviors. Two groups of patients with brain injuries either including or excluding the right hemisphere PPC and a group of healthy subjects performed a visually-directed walking task, in which the subject views a target and then attempts to walk to it without vision. All groups walked without vision accurately and precisely to remembered targets up to 6 m away; the patient groups also performed similarly to the healthy controls when indicating egocentric distances using non-motoric responses. These results indicate that the right PPC is not critically involved in monitoring and integrating non-visual self-motion signals, at least along linear paths. In addition, visual perception of egocentric distance in multi-cue environments is immune to injury of a variety of brain areas. 7

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Role of the posterior parietal cortex in updating reaching movements to a visual target

Cited by 728 publications

References 32 publications

Tracking post-error adaptation in the motor system by transcranial magnetic stimulation

Tracking post-error adaptation in the motor system by transcranial magnetic stimulation

10 years of illusions.

Intact spatial updating during locomotion after right posterior parietal lesions

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