Role of trapped air in the formation of cell-and-protein micropatterns on superhydrophobic/superhydrophilic microtemplated surfaces

Huang, Qiaoling; Lin, Lu‐Yin; Yang, Yun Jung; Hu, Ren; Vogler, Erwin A.; Lin, Changjian

doi:10.1016/j.biomaterials.2012.08.017

Cited by 76 publications

(56 citation statements)

References 43 publications

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“…Because the isoelectric point of TiO 2 is 5−6 under neutral pH conditions and the pH environment of SBF is around 7.40, the Ti−OH groups on the surface are negatively charged and then selectively attract the positively charged Ca 2+ cations. 27 With the increased amount of Ca 2+ cations, the surface becomes positively charged and subsequently adsorbs negatively charged PO 4 3− anions to form apatite nuclei for further apatite precipitation. 25,27 However, it is noticeable that the apatite-inducing ability on the MS-450−OCP was significantly enhanced in comparison to that of the MS-450, which is attributed to the contribution of the OCP thin layer.…”

Section: Resultsmentioning

confidence: 99%

Effect of Octacalcium-Phosphate-Modified Micro/Nanostructured Titania Surfaces on Osteoblast Response

Jiang¹,

Liang²,

Song³

et al. 2015

ACS Appl. Mater. Interfaces

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Surface structures and properties of titanium implants play a vital role in successful bone replacement. To mimic the natural bone structure, some strategies have recently focused on the preparation of multiscaled morphology on medical titanium and shown some promising results; however, relatively few efforts have been made for further enhancing the biocompatibility of such a hierarchical hybrid structure without compromising the superior bioactivity of the starting micro/nano roughness. In this study, a thin ribbonlike octacalcium phosphate (OCP) coating was electrodeposited on a hierarchically structured titania surface, maintaining its micro/nanospongelike morphology. It is indicated that the micro/nanostructured surface with deposited OCP showed an improved biomineralization ability, in comparison to that without OCP modification, when immersed in simulated body fluid (SBF). Further evaluations of cellular activities demonstrated that the introduction of OCP to the micro/nano spongelike-structured surface remarkably enhanced MC3T3-E1 cell proliferation, alkaline phosphatase activity, and extracellular matrix mineralization compared to that of cells on the micro/nanospongelike titania surface during 14 days of culturing. Meanwhile, the OCP-deposited micro/nanostructured surface displayed much a smaller passive current density and lower current response to the applied potential, resulting in the improvement of corrosion resistance. All of the evaluations suggested that the modification of the OCP coating on the prepared micro/nanospongelike titania is of superior chemical stability, biomineralization, and osteoblast activities, which indicates a favorable implant microenvironment for osseointegration in vivo.

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Section: Resultsmentioning

confidence: 99%

Effect of Octacalcium-Phosphate-Modified Micro/Nanostructured Titania Surfaces on Osteoblast Response

Jiang¹,

Liang²,

Song³

et al. 2015

ACS Appl. Mater. Interfaces

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“…82 Medical biopolymers such as silicone, polyurethane, PP, polystyrene, and various biodegradable polymers are often used in medical devices (heart valves, suture materials, syringes or dialysis systems, etc. Figure 9, several studies have shown the positive effects of these new surfaces on pathogenic bacterial adsorption, 86,87 cell-and-protein interaction and adhesion, 88 and bacterial adhesion on elastomeric superhydrophobic surfaces.…”

mentioning

confidence: 99%

Fabrication and Medical Applications of Lotus-leaf-like Structured Superhydrophobic Surfaces

임진익¹,

김승일²,

정영미³

et al. 2013

Polymer Korea

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Various biomaterials have been widely used for biomedical applications, including bio-organs, medical devices, and clinical devices like vessel, blood pumps, artificial kidneys and hearts, even in contact with blood. The issue of blood compatibility has been studied intensively to prevent negative effects such as thrombosis due to the implanted devices. The use of lotus-leaf-like structured surfaces has been extended to an increasing number of applications such as contamination prevention and anticorrosion applications. Various methods such as template, sol-gel transition, layer-bylayer, and other methods, developed for the fabrication of lotus-leaf-like surfaces have been reported for major industrial applications. Recently, the non-wettable character of these surfaces has been shown to be useful for biomedical applications ranging from blood-vessel replacement to antibacterial surface treatment. In this review, we provide a summary of current and future research efforts and opportunities in the development and medical applications of lotus-leaf-like structure surfaces.

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“…It is widely accepted that trapped air is an important property of superhydrophobic materials [36,42]. In this study, it was unable to collect stable EIS data due to air trapped within interstices of superhydrophobic nanotubes (Fig.…”

Section: Corrosion Resistance Of Superhydrophilic and Superhydrophobimentioning

confidence: 96%

“…All experiments were executed at 37 o C. For superhydrophobic materials, an ultrasonic method in Tyrode solution was applied to remove trapped air from the interstices of nanotube surfaces. Experimental details for de-aeration have been previously detailed in reference [36]. Briefly, superhydrophobic samples were immersed in Tyrode solution and ultrasonication was applied for several seconds.…”

Section: Electrochemical Measurementsmentioning

confidence: 99%

“…Superhydrophilic (water contact angle below 5°) and superhydrophobic (water contact angle above 150°) surfaces attract extensive interest because of their potential applications [29], such as self-cleaning [30,31], patterning template [32,33] and protein/cell micropatterning [33][34][35][36]. TNTs are usually superhydrophilic [24,35], and can greatly improve hemocompatibility or corrosion resistance as discussed above.…”

Section: Introductionmentioning

confidence: 98%

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Reduced platelet adhesion and improved corrosion resistance of superhydrophobic TiO2-nanotube-coated 316L stainless steel

Huang

Yang

et al. 2015

Colloids and Surfaces B: Biointerfaces

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110

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Role of trapped air in the formation of cell-and-protein micropatterns on superhydrophobic/superhydrophilic microtemplated surfaces

Cited by 76 publications

References 43 publications

Effect of Octacalcium-Phosphate-Modified Micro/Nanostructured Titania Surfaces on Osteoblast Response

Effect of Octacalcium-Phosphate-Modified Micro/Nanostructured Titania Surfaces on Osteoblast Response

Fabrication and Medical Applications of Lotus-leaf-like Structured Superhydrophobic Surfaces

Reduced platelet adhesion and improved corrosion resistance of superhydrophobic TiO2-nanotube-coated 316L stainless steel

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