"Rotavirus" in Gastroenteritis

White, Griffin; Ashton, C.I.; Roberts, C.; Parry, Huw

doi:10.1016/s0140-6736(74)93308-x

Cited by 22 publications

(5 citation statements)

References 1 publication

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“…This suggests that they usually cause some disruption to gut function, though the extent to which they may be denizens of hospitals, infecting babies soon after admission, needs to be investigated. Ward cross-infection might explain the wide variation in positivity rates in babies with diarrhoea in hospital, ranging from 57% (Middleton et al, 1977) to less than 20% (White et al, 1974;Schoub et al, 1975).…”

Section: Infection and Diseasementioning

confidence: 99%

Viruses in the stools.

Madeley¹

1979

J Clin Pathol

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It has long been possible to isolate viruses from the stools by culture, though the viruses found are rarely implicated in disease of the gut. In contrast, only recently has it been possible to identify viruses in the stools of patients with diarrhoea. Initially, such identifications were made by electron microscopy but the unsuitability of the microscope for large-scale screening has led to the development of other methods. The new methods have concentrated on rotaviruses but other viruses are also implicated and an overall view of the significance of finding a virus in any stool specimen has to take into account the evidence about all viruses, old and new.

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Section: Infection and Diseasementioning

confidence: 99%

Viruses in the stools.

Madeley¹

1979

J Clin Pathol

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“…Ever since Kapikian et a1 [1972] identified a 27-nm particle as the etiological agent of Norwalk gastroenteritis, electron microscopy has revealed a number of other gastroenteritis-associated viruses in human stool specimens [Flewett et al, 1973;Appleton and Higgins, 1975;Caul and Clarke, 1975;Davidson et al, 1975;Madeley and Cosgrove, 1975;Patterson et al, 1975;Schoub et al, 1975;Caul et al, 1977;Middleton et al, 1977;McLean et al, 1977;Kjeldsberg, 1977;Madeley et al, 1977;Echeverria et al, 1977;Appleton et al, 1977;Cameron et al, 1978;Spratt et al, 1978;Chiba et al, 1979;Suzuki et al, 1979;Taraska et al, 1979;Taniguchi et al, 1979;Puel et al, 1979;Goldwater, 19791, including the common-ly described rotavirus [Bishop et al, 1974;Flewett et al, 1974;Holmes et al, 1974;Kapikian et al, 1974;Middleton et al, 1974;White et al, 1974;Bryden et al, 1975;Holmes et al, 1975;Murphy et al, 1975;Albrey et al, 1976;Kapikian et al, 1976;Totterdell et al, 1976;Von Bonsdorff et al, 1976;Birch et al, 1977;Esparza et al, 1977;Murphy et al, 1977;Portnoy et al, 1977;Rodriguez et al, 1977;<...>…”

Section: Introductionmentioning

confidence: 99%

The 30‐ to 54‐nm rotavirus‐like particles in gastroenteritis: Incidence and antigenic relationship to rotavirus

Payne

Ray

Yolken

1981

Journal of Medical Virology

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The 30- to 54-nm rotavirus-like particles were observed in the stool specimens of 17 children with gastroenteritis. These small rotavirus-like particles were shown to be antigenically related to the commonly described 68-nm rotavirus using the techniques of immune electron microscopy and ELISA (enzyme-linked immunosorbent assay). Four specimens containing the small rotavirus-like particles were shown to contain an antigen of a common human rotavirus serotype (type 2). The findings of small rotavirus-like particles of different diameters sharing a common antigen with rotavirus type 2 cautions against the naming of new candidate viruses based on morphology alone. In addition, the shedding of pure populations of single-shelled rotaviruses, herein described, could be an unusual phenomenon which may occur only sporadically. The relationship of the smaller rotavirus-like particles to rotavirus morphogenesis is discussed.

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“…The early techniques involved the use of density gradients to clarify and concentrate small round virus particles prior to immune electron microscopy [1,2]. Many other candidate viruses have been reported using a similar technique [6][7][8][9][10][11][12]. Many other candidate viruses have been reported using a similar technique [6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%