This paper studies reliability of probabilistic neighbor-aware gossip algorithms over three wellknown large-scale random topologies, namely Bernoulli (or Erdős-Rényi) graph, the random geometric graph, and the scale-free graph. We propose a new and simple algorithm which ensures higher reliability at lower message complexity than the three families of gossip algorithms over every topology in our study.We also present a uniform approach to model the reliability of probabilistic gossip algorithms in the different random graphs, whose properties, in fact, are quite different. In our model a forwarding probability is derived with consideration of parameters in gossip algorithms and graph properties. Our simulations show that our model gives a reasonable prediction of the trade-off between reliability and message complexity for all probabilistic neighbor-aware gossip algorithms in various random networks. Therefore, it allows to fine-tune the input parameters in the gossip protocols to achieve a desirable reliability with tolerable message complexity.