2023
DOI: 10.1002/sim.9812
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Rule ensemble method with adaptive group lasso for heterogeneous treatment effect estimation

Abstract: The increasing scientific attention given to precision medicine based on real‐world data has led to many recent studies clarifying the relationships between treatment effects and patient characteristics. However, this is challenging because of ubiquitous heterogeneity in the treatment effect for individuals and the real‐world data on their backgrounds being complex and noisy. Because of their flexibility, various machine learning (ML) methods have been proposed for estimating heterogeneous treatment effect (HT… Show more

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Cited by 5 publications
(3 citation statements)
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“…It also enables an initial understanding of the operational mechanism of the intelligent model through the analysis of principal rules (Friedman and Popescu, 2008). Specifically, given a marine data sample x = {x 1 ,x 2 ,…,x n } T ∈ R n , the RuleFit model is defined as follows (Wan et al, 2023) (Equation 4):…”
Section: Model Computationmentioning
confidence: 99%
“…It also enables an initial understanding of the operational mechanism of the intelligent model through the analysis of principal rules (Friedman and Popescu, 2008). Specifically, given a marine data sample x = {x 1 ,x 2 ,…,x n } T ∈ R n , the RuleFit model is defined as follows (Wan et al, 2023) (Equation 4):…”
Section: Model Computationmentioning
confidence: 99%
“…To arrive at a more effective solution strategy, it is advisable to employ multiple commonly used variable selection methods separately and integrate the common factors among these methods. Notably, some scholars have expanded the concept of ensemble learning to include group variable selection algorithms (Wang [ 34 ], 2022; Wan and Tanioka [ 35 ], 2023; Hussein and Rahul [ 36 ], 2023). To accommodate more complex group structures, Thompson (2021) [ 37 ] proposed a sparse estimator of group structure by combining group subset selection and shrinkage.…”
Section: Introductionmentioning
confidence: 99%
“…Wan et al. 17 proposed a RuleFit-based method to estimate the HTE; however, it does not consider the prognostic effect. By contrast, the proposed method considers the prognostic effect in estimating HTE, thereby allowing for a more refined interpretation of the treatment effect.…”
Section: Introductionmentioning
confidence: 99%