“…Overall, the majority of studies have demonstrated high sensitivity and specificity of oral fluid-based rapid HIV test in comparison with routinely utilized methods. [15] Clinical perspective of the article V arious studies have been conducted in the field of saliva in HIV patients, such as detection of salivary pH, buffer capacity, nitric oxide, antioxidants , and early detection of oral lesions. hence the future scope of the research is to analyze the CD4 levels in the saliva that can help in the early diagnosis of the immunodeficiency syndrome.…”