Salivary gland tumors in canadian eskimos

Wallace, A. C.; MacDougall, Julie; Hildes, J. A.; Lederman, J. M.

doi:10.1002/1097-0142(196310)16:10<1338::aid-cncr2820161015>3.0.co;2-e

Cited by 69 publications

(17 citation statements)

References 7 publications

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“…It is estimated at 0.5 to 2 percent of all neoplasia [3][4][5]. Overall incidence of these tumours in different geographical locations is substantially the same except in Canada, where the condition is unusually prevalent in excess among Eskimos [6]. Location wise, Parotid gland is involved in about eighty percent (80%) of salivary tumours, however it is reported that the Chinese origin Malaysians show great preponderance for submandibular glands [1], Ugandans over palate [2] and people of West Indies over the sublingual and minor salivary glands [7].…”

mentioning

confidence: 99%

A Pathological Study of Benign and Malignant Tumours of Salivary Glands

Chatterjee

Panda

2000

Medical Journal Armed Forces India

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confidence: 99%

A Pathological Study of Benign and Malignant Tumours of Salivary Glands

Chatterjee

Panda

2000

Medical Journal Armed Forces India

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“…Geographic variation, with a high risk among Eskimos (Wallace et al, 1963;Lanier et al, 1976) and residents of Scotland (Lennox et al, 1978), suggests other as yet unidentified factors. Experimental studies in mice have demonstrated a high risk of salivary gland malignancy after infection with polyoma virus (Gross, 1953).…”

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confidence: 99%

Second primary malignancies following salivary gland cancers

Biggar¹,

Curtis²,

Hoffman³

et al. 1983

Br J Cancer

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“…T h e most striking difference between this study and those from other parts of the Arctic is the complete absence of parotid malignancies in Southwestern Alaska. Wallace et al 15 who reported 11 cases of this type, state that these tumors accounted for 28% of all cancers in Canadian Eskimos known to them. A squamous cell carcinoma thought to have arisen in the submaxillary gland was the only salivary gland malignancy encountered in the Yukon-Kuskokwim Delta.…”

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confidence: 99%

Characteristics of cancer in the eskimos of Southwestern Alaska

Fortuine¹

1969

Cancer

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Using records from the Public Health Service Alaska Native Hospital at Bethel, Alaska, the author reviews all known cancers occurring among the Yupik Eskimos of Southwestern Alaska during the 101/2 year period from July 1957 through December 1967. Since this facility is the source, direct or indirect, of virtually all medical care provided to a well‐defined population, these records can be used for a reasonably accurate estimate of incidence, mortality, and other epidemiologic characteristics of cancer in this group. The 85 tumors in the series give a crude incidence of 82.4/100,000 for males and 106.3/100,000 for females. Forty‐six per cent of the total number originated in the alimentary tract. In both sexes, the commonest cancer site was the esophagus. Another common site in both sexes was the kidney, as was the thyroid in females. There were 45 deaths from cancer, including one person with two separate advanced malignancies. Standardized mortality ratios for cancer were calculated for the Eskimos and other populations based on the U.S. Caucasian death rates for 1962. Those for Yupik Eskimo males and females were 73 and 79, respectively (U. S. Caucasian = 100), for histologically proven cases and 84 and 94, respectively, for all diagnosed cases. A comparison of observed with expected cancer deaths (based on U.S. Caucasian rates for 1962–63) revealed a great excess of esophageal cancer in the Eskimos of both sexes. Further study of this problem, with particular reference to possible causative factors in traditional Eskimo cultural practices, seems warranted. Despite widespread opinion to the contrary, cancer is a relatively common disease in Eskimos and an increasingly serious and expensive health problem in the north.

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Salivary gland tumors in canadian eskimos

Cited by 69 publications

References 7 publications

A Pathological Study of Benign and Malignant Tumours of Salivary Glands

A Pathological Study of Benign and Malignant Tumours of Salivary Glands

Second primary malignancies following salivary gland cancers

Characteristics of cancer in the eskimos of Southwestern Alaska

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