Salmonella septic arthritis in a patient with Crohnʼs disease on infliximab

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

“…Salmonellosis is treated with antibiotics such as fluoroquinolones or third-generation cephalosporins. In cases of S. typhimurium osteomyelitis, [351] aortitis, [352] or septic arthritis, [353,354] a combination of antibiotics and surgical treatment may be required. Immunosuppressants should be temporarily withheld until resolution of active infection.…”

Ultrasound Detection of Salmonella Septic Arthritis in a Rheumatoid Arthritis Patient on Anti-TNF Treatment

“…It rarely causes primary infection in the musculoskeletal system except in special circumstances such as following instrumentation, traumatic injury to the joint, or arthrocentesis. The risk of Salmonella septic arthritis is associated with infancy, elderly, or with diseases such as sickle cell anemia, 18 - 21 acute lymphoblastic leukemia, 22 , 23 thalassaemia, 24 , 25 idiopathic thrombocytopenic purpura, 26 Crohn’s disease, 27 systemic lupus erythematosus, 28 , 29 HIV, 30 RA, and diabetes mellitus, 31 or in special circumstances such as prosthetic joint, 32 - 36 transplant, 37 or avascular necrosis. It can also cause osteomyelitis septic arthritis or postinfectious reactive arthritis.…”

Bacterial Intestinal Superinfections in Inflammatory Bowel Diseases Beyond Clostridum difficile

“…There are some data suggesting that Salmonella can complicate IBD course, 67,68 whereas one study showed that S. enteritidis exposure did not worsen outcome in CD patients. 69 Salmonella has also shown to cause osteoarticular complications such as arthritis 70 and osteomyelitis 71 in IBD patients, mimicking IBD not only in digestive but also extraintestinal manifestations. In a Chilean study, S. enteritidis exposure was associated with smoking habit and not with IBD disease activity.…”