SARS-CoV-2 molecular identification and clinical data analysis of associated risk factors from a COVID-19 testing laboratory of a coastal region in Bangladesh

Ali, Roushan; Chowdhury, Md. Rayhan; Mas-ud, Md. Atik; Islam, Saidul; Shimu, Ajmeri Sultana; Mina, Fahmida Begum; Sharmin, Nur E; Hasan, Md. Faruk

doi:10.1016/j.heliyon.2021.e06650

Cited by 3 publications

(8 citation statements)

References 29 publications

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“…Our analysis observed that 28.53% of COVID-19 patients were between the ages of 21 and 30, which may reflect the busiest part of life, such as when they had to go out for office or business and were primarily infected. A similar study reported that the highest percentage (51.80%) of SARS-CoV-2 infected patients were observed in the 20–40 years old age range [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…Male domination in COVID-19 instances could be due to gender disparities in testing patients, women’s shyness, and a more active male population than the female population in our country, particularly in terms of jobs outside the home. A recent regional demographic investigation showed that males (56.8%) had been infected 13.6% higher than females (43.2%) [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…However, several past studies showed that urban people were more vulnerable to COVID-19 than rural people due to the population density of the urban area [ 33 , 34 ]. Ali et al reported recently that the prevalence of COVID-19 infected patients is clearly higher in urban areas (52.7%) than in rural areas (47.3%) [ 1 ]. We found that asymptomatic cases were reasonably higher in the house where more than 4 people lived together.…”

Section: Discussionmentioning

confidence: 99%

“…An outbreak of 2019-novel coronavirus infection, a disease called the new coronavirus pneumonia (NCP) caused by the SARS-CoV-2, initially referred to as 2019-nCoV and later referred to as COVID-19 by the World Health Organization (WHO) on 11 February 2020 [ 1 ], has spread worldwide through human transmission since the first case in December 2019. The World Health Organization (WHO) on 11 March 2020 declared COVID-19 a pandemic [ 2 ], pointing to the over 173,482,886 infected cases and 3,731,539 deaths of the coronavirus affliction in over 218 countries and territories around the world till 5th June 2021 and the sustained risk of further global spread through the second-wave of infections ( https://www.worldometers.info/coronavirus/ ).…”

Section: Introductionmentioning

confidence: 99%

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Clinical manifestations and socio-demographic status of COVID-19 patients during the second-wave of pandemic: A Bangladeshi experience

Ali¹,

Hasan²,

Rahman³

et al. 2021

Journal of Infection and Public Health

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Background Bangladesh is a densely populated country with a substandard healthcare system and a mediocre economic framework. Due to the enormous number of people who have been unaware until now, the development of COVID-19’s second-wave infection has become a severe threat. The present investigation aimed to characterize the clinical and socio-demographic characteristics of COVID-19 in Bangladesh. Methods A cross-sectional analysis was carried out from all the other COVID-19 patients and confirmed by RT-PCR undergoing a specialized COVID-19 hospital. From March 1 to April 15, 2021, a total of 1326 samples were collected. Samples were only obtained from non-critical COVID-19 patients as critically ill patients required emergency intensive care medications. Then, from April 17 to May 03, 2021, SARS-CoV-2 infection and clinical assessment was performed based on interim guidelines from the WHO. The diagnosis was conducted through RT-PCR. Later, identifying the symptomatic and asymptomatic patient based on checking the Clinical Observation Form (COF). The patients filled the COF form. Finally, statistical analyses were done using the SPSS 20 statistical program. Results In this investigation, a total of 326 patients were diagnosed as COVID-19 positive. Among them, approximately 19.02% (n = 62) were asymptomatic, and 80.98% (n = 264) were symptomatic. Here, the finding shows that the occurrence of this infection was varied depending on age, sex, residence, occupation, smoking habit, comorbidities, etc. However, Males (60.12%) were more affected than females (39.88%), and, surprisingly, this pandemic infected both urban and rural residents almost equally (urban = 50.92%; rural = 49.08%). Approximately 19% of the asymptomatic and 62% of symptomatic cases had at least one comorbid disorder. Interestingly, an unexpected result was exhibited in the case of smokers, where non-smokers were more affected than smokers. The study indicates community transmission of COVID 19, where people were highly infected at their occupations (35.58%), at houses (23.93%) and by traveling (12.88%). Noteworthy, according to this report, a large number (19.33%) of individuals did not know exactly how they were contaminated with SARS-CoV-2. Patients were most commonly treated by an antibiotic 95.09%, followed in second by corticosteroid 46.01%. Anti-viral drugs, remdesivir, and oxygenation are also needed for other patients. Among those, who were being treated, approximately 69.33% were isolated at home, 27.91% were being treated at dedicated COVID-19 hospitals. Finally, 96.63% were discharged without complications, and 0.03% has died. Conclusion This investigation concludes that males became more infected than females. Interestingly, both urban and rural people became nearly equally infected. It noticed community transmission of SARS-CoV-2, where people were highly infected at their workplaces. A higher rate of silent transmissio...

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical manifestations and socio-demographic status of COVID-19 patients during the second-wave of pandemic: A Bangladeshi experience

Ali¹,

Hasan²,

Rahman³

et al. 2021

Journal of Infection and Public Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…Despite of these measures,COVID-19 cases have spread to all 64 districts of Bangladesh 6 . The situation became more challenging due to noncompliance of people toward the universal protective measures, emergence of mutant variants of SARS-CoV-2and a second wave strike of COVID-19 in Bangladesh 9,10,11 . In Bangladesh, by 20 th September, 2021, about 1,542,683 confirmed COVID-19 cases with 27, 225 deaths were reported 5 .…”

Section: Introductionmentioning

confidence: 99%

Demographic Profile of COVID-19 Cases: Laboratory Experience in a Tertiary Care Hospital of Dhaka City

Khan

Afroz

Mohiuddin

et al. 2022

Sir Salimullah Med. Coll. J.

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Background: COVID-19 pandemic becomes a great threat due to continuous rise of the global incidence and emergence of multiple waves of infections in many countries of the world. The diversity of this infection varies from country to country and knowledge regarding demographic characteristics of this infection is essential to combat the pandemic situation. Objective: The aim of this study was to characterize the demographic profile of rRT-PCR (real time reverse transcriptase-polymerase chain reaction) confirmed COVID-19 cases and to provide a timeline regarding rates of infection. Materials and methods: This cross- sectional study was conducted at the Department of Virology of Sir Salimullah Medical College, Dhaka, Bangladesh from May, 2020 to April, 2021. rRT-PCR test was performed to detect SARS-COV2 in 35001 clinical samples and their demographic characteristics were analyzed. Results: Out of 35001 suspected cases,5008 (14.3%) were tested positive of which 58.0% belongs to the age group between 18–45 years.The majority of the cases were male (69.0%). Most of the positive cases became negative (85.0%) within three weeks of infection by rRTPCR test. The highest percentage (29.2%) of confirmed COVID-19 cases was reported in the month of May 2020, then gradual decrease in the subsequent months followed by a sharp rise to 27.2% in the month of March, 2021. Conclusion: This study shows an overall 14.3% positivity among suspected COVID-19 cases where adult males between 18-45 years are more commonly suffered. However, most of the infected persons become rRT-PCR negative within three weeks’ time. A second surge of SARS-COV2 infection has been documented in this study that coincided with second wave of COVID-19 in Bangladesh. Sir Salimullah Med Coll J 2022; 30: 9-13

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A critical review of research methodologies for COVID-19 transmission in indoor built environment

Haowei,

Mahyuddin,

Bin Nik Ghazali

et al. 2024

International Journal of Environmental Health Research

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SARS-CoV-2 molecular identification and clinical data analysis of associated risk factors from a COVID-19 testing laboratory of a coastal region in Bangladesh

Cited by 3 publications

References 29 publications

Clinical manifestations and socio-demographic status of COVID-19 patients during the second-wave of pandemic: A Bangladeshi experience

Clinical manifestations and socio-demographic status of COVID-19 patients during the second-wave of pandemic: A Bangladeshi experience

Demographic Profile of COVID-19 Cases: Laboratory Experience in a Tertiary Care Hospital of Dhaka City

A critical review of research methodologies for COVID-19 transmission in indoor built environment

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