Sciatic and peroneal nerve injuries

Abstract

In the past, the attitude toward surgical repair of sciatic and peroneal nerve lesions was excessively pessimistic. Refinements of microsurgical technique, nerve conduction studies, and the establishment of indications and optimal timings for surgical interventions have led to significant improvements in outcomes, making repair worthwhile in most cases. Tendon transfers can augment functional outcomes, and are performed as secondary procedures or (in selected cases) in combination with the initial repair. Developments in the basic sciences, bioengineering, and medical imaging may further improve the results of management of these serious nerve injuries.

An Evidence-Based Structured Review to Assess the Results of Common Peroneal Nerve Repair

“…51,52 Investigative techniques have also improved with the recent development of magnetic resonance neurography for more accurate evaluation of nerve injuries. 8 With these recent advancements, we can expect to see a significant improvement for common peroneal and other peripheral nerve repairs in the future.…”

“…Regular physiotherapy would be necessary during the postoperative period, as this serves to prime the denervated effector muscles for reinnervation and maintain passive range of motion. 8 Korompilias and colleagues 8 suggested using splints in the long term to prevent contractures. Electromyelography may be used, bearing in mind that electromyography signs of recovery often precede clinical recovery by some months.…”

The effect of collagen-binding NGF-β on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model

“…Prolonged sitting or lying with pressure on the buttocks may also injure it. Systemic diseases, such as diabetes, can typically damage many different nerves, including the sciatic nerve [1,2]. Numerous therapeutic interventions have been tested to enhance functional recovery after sciatic nerve injuries.…”

Linear Ordered Collagen Scaffolds Loaded with Collagen-Binding Basic Fibroblast Growth Factor Facilitate Recovery of Sciatic Nerve Injury in Rats

“…1 It may result in the partial or total loss of motor, sensory, and autonomic functions, and therefore have a marked negative impact on the quality of life. 2,3 Natural biological functional scaffolds, consisting typically of biological materials filled with promoting elements, have been developed to elicit axon regeneration after peripheral nerve injury. There have been several reports of their use to promote peripheral nerve repair.…”