Research on Vlogs, ethnoscience, and social media literacy, is one of the trends in the era of the industrial revolution 4.0, so it is exciting to research. However, scientific studies are still relatively new and rare. A systematic review is not yet available. Thus, the purpose of this study was to analyze the review content of synthesized articles with a focus on the study of the authors' origin, aims, method variations, and findings. This research's data collection method adopted the PRISMA design, consisting of four steps: identification, screening, eligibility, and inclusion. Article searches are carried out using the publish or perish application directly linked to Google Scholar search. The total number of articles found was 2971 articles in the period 2016 to 2020. This study was decided to review 25 articles with the distribution of 8 Vlog, 6 ethnosciences, and 11 social media literacy. The results showed that (1) Indonesia was the country that was ranked first out of nine countries on the topics of Vlog by 75% and ethnoscience topics by 67%, (2) the purpose of the research is on average testing, finding and developing topics with other variables, (3) the research methods also used varied, including descriptive qualitative, quasi-experimental, exploratory, survey, literature review, and R&D, (4) The findings indicate that these topics are interesting to study because they have a positive effect on learning, increasing learning motivation, self-confidence, speaking skills, understanding concepts, and critical thinking skills, innovative, creative to the entrepreneurial character.