Screening for Second Primary Lung Cancer After Treatment of Laryngeal Cancer

Abstract

Screening by chest x-ray examination to detect lung cancer in an asymptomatic stage after curative treatment for squamous cell laryngeal cancer does not improve survival for patients who develop lung cancer.

Second Primary Lung Cancer with Glottic Laryngeal Cancer as Index Tumor – A Case Report

“…All head and neck cancer patients should be routinely screened using chest X-rays for early detection of a second primary lung cancer [12]. But screening by chest X-rays has failed to improve survival in patients with secondary lung cancer [12]. Screening for lung cancer by CT scan has a higher detection rate as compared to chest X-rays [13,14].…”

Clinical Factors Related to Suspected Second Primary Lung Cancer Development in Patients with Head and Neck Cancer

“…Hence, early detection of a second primary lung cancer may be important for prolonging the survival of patients with HNC. All head and neck cancer patients are routinely screened at initial diagnosis using chest x-rays for early detection of a second primary lung cancer (8). Some clinicians will also perform comprehensive bronchoscopy, with or without bronchial washing, to evaluate the possibility of a second primary lung cancer (9).…”

Primary lung cancer after treatment of head and neck cancer without lymph node metastasis: Is there a role for autofluorescence bronchoscopy?

“…Patients with curatively treated HNC are followed regularly to facilitate early detection of locoregional recurrence to allow salvage surgery [8], and for second primary tumors. Although prospective data have not demonstrated significant survival benefit following treatment of asymptomatic recurrences or second primary lung cancers (SPLCs) detected during close surveillance [6,9,10], others have indicated better outcome for patients diagnosed early with limited disease who still retain the option for future intervention [11,12].…”