Screening of Anticancer Properties of some Medicinal Plants - Review

Abstract

Cancer is the most deadly disease in the world and cancer deaths are increasing rapidly in developed and developing countries. There are many types of cancer affecting people of all ages with no discrimination of age and sex. Treatment options are synthetic drugs and naturally derived drugs. The synthetic drugs have many side effects and are not preferred and there is a dire need to have a natural anticancer drug with novel mechanism of action. The plant kingdom with its vast diversity, rich secondary metabolites, easy availability makes them most popular for discovering new anticancer compounds. With this idea, in this review, 50 medicinal plants belonging to 34 families were screened for their anticancer properties. They were used as plant extracts or essential oils or metal nanoparticles. Detailed information is also given regarding the part used, solvent used, assay and cell lines used for evaluating the anticancer properties. These are promising plants and hence potential candidates for further studies which may ultimately lead to new drugs or lead molecules for drug development to be used as natural, novel and safe anticancer agents. K e y w o r d sMedicinal plants, anticancer activity, MTT assay, cell lines, in vitro methods

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