Second-generation colon capsule endoscopy is feasible in the out-of-clinic setting

Adler, Samuel N.; Hassan, Cesare; Metzger, Yoav C.; Sompolinsky, Yishai; Spada, Cristiano

doi:10.1007/s00464-013-3206-y

Cited by 24 publications

(15 citation statements)

References 13 publications

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“…First‐generation CCE (CCE‐1) has some technical differences from the small‐bowel capsule, being approximately 6 mm longer with dual cameras that can acquire images from both ends, optics with more than twice the coverage area of the small‐bowel capsule, automatic light control, and a rate of 4 frames/s. CCE has been mainly used for colorectal cancer screening . Table shows the diagnostic accuracy of CCE for significant findings (polyps ≥6 mm or ≥3 polyps).…”

Section: Colon Cementioning

confidence: 99%

“…CCE has been mainly used for colorectal cancer screening. [84][85][86][87][88][89][90] Table 2 shows the diagnostic accuracy of CCE for significant findings (polyps ≥6 mm or ≥3 polyps). Van Gossum et al 84 reported that CCE-1 has a moderate sensitivity (64%) and specificity (84%) compared with colonoscopy for surveillance of colorectal neoplasia.…”

Section: Colon Cementioning

confidence: 99%

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Current status of capsule endoscopy through a whole digestive tract

Hosoe

Ogata

2014

Digestive Endoscopy

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More than a decade has passed since small-bowel capsule endoscopy (CE) was first reported. Small-bowel CE is a non-invasive tool that allows visualization of the entire small-intestinal mucosa and facilitates detection of small-intestinal abnormalities. Several studies have shown benefit of small-bowel CE for certain disorders. Because it is non-invasive, CE has been applied to other organs including the esophagus, stomach, and colon. The main indications for esophageal CE (ECE) are screening for gastroesophageal reflux disease/Barrett's esophagus, and esophageal varices. However, the clinical benefit of ECE is unconfirmed. Magnetically guided CE (MGCE) was developed to visualize the gastric mucosa. MGCE is a new concept with room for improvement of capsule navigation and the preparation protocol. Recently, two new small-bowel CE tools were released. First-generation colon CE (CCE-1) has moderate sensitivity and specificity compared with colonoscopy for colorectal neoplasia surveillance. To obtain higher accuracy, a second-generation CCE (CCE-2) was developed with a high sensitivity for detecting clinically relevant polypoid lesions. A possible application of CCE is for inflammatory bowel disease. In the near future, CE may include diagnostic and therapeutic functions such as magnifying endoscopy systems, targeted biopsy forceps, and drug delivery systems.

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Section: Colon Cementioning

confidence: 99%

Section: Colon Cementioning

confidence: 99%

Current status of capsule endoscopy through a whole digestive tract

Hosoe

Ogata

2014

Digestive Endoscopy

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“…The sensitivity of CCE-1 for the detection of polyps was low with 7 (26%) cases out of 27 histologically diagnosed with CRC, being negative [15]. In contrast Conversely with CCE-2 no case of missed CRC was reported as shown in Table 2 [8][9][10][11][12][20][21][22]. In one study [20], two patients with CRC diagnosed by CCE-2 were referred for surgery without undergoing OC.…”

Section: Accuracy Of Cce-2 For Polyp and Crc Detectionmentioning

confidence: 99%

“…Eliakim [8] 98 78 81 Spada [9] 117 81 88 Rondonotti [11] 50 70 72 Hagel [12] 24 90 71 Negreanu [20] 70 72 77 Farnbacher [21] 65 N.R. 74 Adler [22] 41 95 85 N.R., not reported. [29], thus preventing the application of the same system of classification.…”

Section: Authormentioning

confidence: 99%

Colorectal polyp diagnosis: results with the second‐generation colon capsule (CCE‐2)

Rondonotti

Pennazio

2014

Colorectal Disease

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“…[ 36 ]), Gastroenterology—1608 articles (e.g. [ 37 ]), Hepatology—875 articles ([ 38 ]), Oncology and Surgery—763 and 744 articles respectively ([ 39 , 40 ]). As shown in Table 1 and above, the area of research devoted to capsule endoscopy is essentially associated with medicine.…”

Section: Introductionmentioning

confidence: 99%

Overview of technical solutions and assessment of clinical usefulness of capsule endoscopy

Koprowski

2015

BioMed Eng OnLine

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The paper presents an overview of endoscopic capsules with particular emphasis on technical aspects. It indicates common problems in capsule endoscopy such as: (1) limited wireless communication (2) the use of capsule endoscopy in the case of partial patency of the gastrointestinal tract, (3) limited imaging area, (4) external capsule control limitations. It also presents the prospects of capsule endoscopy, the most recent technical solutions for biopsy and the mobility of the capsule in the gastrointestinal tract. The paper shows the possibilities of increasing clinical usefulness of capsule endoscopy resulting from technological limitations. Attention has also been paid to the current role of capsule endoscopy in screening tests and the limitations of its effectiveness. The paper includes the author’s recommendations concerning the direction of further research and the possibility of enhancing the scope of capsule endoscopy.

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Second-generation colon capsule endoscopy is feasible in the out-of-clinic setting

Abstract: As an out-of-clinic procedure, CCE is feasible and easily performed. A home-based procedure may be associated with better acceptability and potentially with increased adherence to Colorectal cancer screening.

Cited by 24 publications

References 13 publications

Current status of capsule endoscopy through a whole digestive tract

Current status of capsule endoscopy through a whole digestive tract

Colorectal polyp diagnosis: results with the second‐generation colon capsule (CCE‐2)

Overview of technical solutions and assessment of clinical usefulness of capsule endoscopy

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