“…[6,7] Moreover, Cremophor EL often causes adverse effects such as hypersensitivity, neurotoxicity, and nephrotoxicity. [8] Conse-quently, in the past few decades, various methods, including the use of PTX-coated nanoparticles, [9][10][11][12][13] polymers, [14,15] inorganic nanomaterials, [16,17] prodrugs, [17] and mesoporous silica nanoparticles, [18][19][20][21] have been developed to improve the anticancer efficacy of PTX.…”