2001
DOI: 10.1017/s1355617701711058
|View full text |Cite
|
Sign up to set email alerts
|

Selective deficits in verbal working memory associated with a known genetic etiology: The neuropsychological profile of Duchenne muscular dystrophy

Abstract: Forty-one boys diagnosed with Duchenne muscular dystrophy (DMD) were each compared to an unaffected sibling on a battery of neuropsychological tests. Verbal, visuospatial, attention/memory, abstract thinking, and academic achievement skills were tested. Results indicated the boys with DMD performed similarly to their siblings on the majority of measures, indicating intact verbal, visuospatial, long-term memory, and abstract skills. However, the DMD group did significantly more poorly than their siblings on spe… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

5
100
3
16

Year Published

2006
2006
2020
2020

Publication Types

Select...
6
1
1

Relationship

1
7

Authors

Journals

citations
Cited by 106 publications
(124 citation statements)
references
References 42 publications
5
100
3
16
Order By: Relevance
“…This study recruited 12 patients [age 9.14±2.52 years (range, 6-13)] with a diagnosis of DMD (confirmed by genetic testing or muscle biopsy) from the DMD Multidisciplinary Outpatient Clinic of CAPF General Hospital, and 14 healthy volunteers [age 9.39±2.99 years (range, [6][7][8][9][10][11][12][13][14]]. Those who had a medical or surgical history of potential impact on neurocognitive functioning (e.g., head injury), were not contactable, or whose parents refused to consent were excluded.…”
Section: Participantsmentioning
confidence: 99%
See 2 more Smart Citations
“…This study recruited 12 patients [age 9.14±2.52 years (range, 6-13)] with a diagnosis of DMD (confirmed by genetic testing or muscle biopsy) from the DMD Multidisciplinary Outpatient Clinic of CAPF General Hospital, and 14 healthy volunteers [age 9.39±2.99 years (range, [6][7][8][9][10][11][12][13][14]]. Those who had a medical or surgical history of potential impact on neurocognitive functioning (e.g., head injury), were not contactable, or whose parents refused to consent were excluded.…”
Section: Participantsmentioning
confidence: 99%
“…The core cognitive deficit in DMD is "limited verbal span" (6). Some researchers have noted that children with DMD have greater difficulty on tests requiring attention to and repetition of verbal material (6)(7)(8)(9)(10). This finding remains consistent regardless of whether children with DMD are compared to normal controls, their siblings, or children with other degenerative muscle diseases.…”
Section: Introductionmentioning
confidence: 96%
See 1 more Smart Citation
“…We have further hypothesized that limited verbal span may be the core deficit in DMD. As deficits in verbal span have been linked to impairments in the acquisition of phonological knowledge and single-word vocabulary (Adams & Gathercole, 2000;Gathercole et al, 1997), this core deficit may also help to explain impairments seen in phonological awareness, reading, and writing found in children with DMD (Billard et al, 1992;Dorman et al, 1988;Hendriksen & Vles, 2006;Hinton et al, 2001Hinton et al, , 2004Leibowitz & Dubowitz, 1981;Worden & Vignos, 1962).…”
Section: Introductionmentioning
confidence: 99%
“…DMD is the most common fatal genetic condition in children [2] with the prevalence of about 1 in 3,600-9,337 live male births worldwide [3,4]. It is neuromuscular disease generally caused by protein truncating mutations in large DMD gene "dystrophin" at Xp21.2 [5,6].…”
Section: Introductionmentioning
confidence: 99%