Selective Unidirectional Horizontal Saccadic Paralysis From Acute Ipsilateral Pontine Stroke

Abstract

This case provides support for the concept that PPRF lesions in humans may selectively impair unidirectional horizontal saccades.

Selective Unidirectional Saccadic Palsy Due to Cavernous Angioma in the Pontine Tegmentum

“…However, to our knowledge the selective unilateral involvement of the PPRF in cavernous angioma is extremely rare. The present case shows that cavernous angioma is a possible cause of selective PPRF lesions and thus a possible etiology of saccadic palsy, together with stroke, metastatic tumor, and tuberculoma 124. Detailed bedside neurological examinations of ocular movements are therefore crucial to ensure a correct diagnosis.…”

“…The anatomical proximity allows the simultaneous involvement of nearby structures such as the medial longitudinal fasciculus and abducens nucleus. Therefore, selective horizontal saccadic palsy due to precise PPRF lesions has rarely been reported 4…”