This study examined diagnostic predictors of prospectively observed suicide attempts in a personality disorder (PD) sample. During 2 years of follow-up, 58 participants (9%) reported at least 1 definitive suicide attempt. Predictors that were examined include 4 PD diagnoses and selected Axis I diagnoses (baseline and course). Multivariate logistic regression analyses indicated that baseline borderline personality disorder (BPD) and drug use disorders significantly predicted prospective suicide attempts. Controlling for baseline BPD diagnosis, proportional hazards analyses showed that worsening in the course of major depressive disorder (MDD) and of
NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript substance use disorders in the month preceding the attempt were also significant predictors. Therefore, among individuals diagnosed with PDs, exacerbation of Axis I conditions, particularly MDD and substance use, heightens risk for a suicide attempt.Personality disorders (PDs) and Axis I disorders, particularly borderline personality disorder (BPD) and major depressive disorder (MDD), have long been established as risk factors for suicidal behavior (e.g., Friedman, Aronoff, Clarkin, Corn, & Hurt, 1983;McGlashan, 1986). However, because the base rates of suicide and suicide attempts are relatively low compared to the base rates of these disorders, diagnoses in and of themselves are of limited use in predicting suicidal events. Furthermore, it is not always clear whether improvement or deterioration of a psychiatric condition (particularly MDD) is the greater risk factor for suicidal behavior. Therefore, alternative means of investigating the predictive utility of psychiatric disorders, such as identifying high-risk combinations of co-occurring Axis I and Axis II disorders, or examining specific changes in the course of a disorder prior to a suicide event, may be more effective.In reviewing suicide research, various types of suicide behaviors need to be distinguished, particularly because each type of behavior is associated with different risk factors. Generally accepted classifications of suicide behavior include completed suicide, suicide attempt, and suicide ideation (Beck, Beck, & Kovacs, 1975;O'Carroll et al., 1996). The consistent findings that men are at greater risk for suicide completion and women are at greater risk for suicide attempt(s) (Hirschfeld & Davidson, 1988) highlight the importance of identifying risk factors specific to the behavior. Nonetheless, because history of past suicide attempt(s) is one of the greater risk factors for suicide completion, research on suicide attempts inevitably informs clinical judgment with regard to suicide completion (e.g., Goldstein, Black, Nasrallah, & Winokur, 1991;Roy, 1982). Furthermore, the distinction between suicide attempts and suicide gestures (or parasuicide) has been advocated on the basis of differing intent to die. Specifically, those who make a suicide gesture (or parasuicide) do not intend to die but do aim either to draw a...