Semen Characteristics and Plasma Levels of Testosterone after Bilateral Vasectomy in Bucks

Batista, M.; Prats, Neus; Calero, P.; González, F.; Cabrera, Fernando; Medrano, A.; Gracia, A.

doi:10.1046/j.1439-0531.2002.00388.x

“…In group I, no significant change (P > 0.05) in testosterone was observed at different postoperative time intervals. It was attributed to bilateral vasectomy, which does not exert a remarkable effect on the steroidogenic functionality of the testicle as also reported by Batista et al (24). In group II, a significant decrease (P < 0.01) in plasma testosterone was observed immediately after the operation up to the 7th postoperative day.…”

Section: Discussionsupporting

confidence: 69%

Laparoscopic Vasectomy vs Laparoscopic Sterilization in Dogs: A Comparison of Two Techniques

Mahalingam¹,

Kumar²,

Maiti³

et al. 2014

WJOLS

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Twelve clinically healthy, adult male dogs randomly equally divided into two groups (I and II). Animals of both the groups received xylazine-ketamine anesthesia. Laparoscopic bilateral vasectomy was performed in group I, whereas in animals of group II in additition to vasectomy, spermatic artery-vein plexus were clipped with titanium clips at a distance of 1 to 2 cm. Insufflation of abdominal cavity was achieved by CO 2 (2 liter/minute) at 10 mm Hg pressure gradient. Clinical observations revealed no significant changes. Differential leukocyte count (DLC) revealed significant neutrophilia and comparative lymphopenia on 3rd postoperative in both groups. Significant increase (p < 0.05) in plasma alkaline and acid phosphatase level was observed on day 3 postoperatively. Indices of oxidative stress viz lipid peroxidation (LPO), catalase (CAT), superoxide dismutase (SOD), reduced glutathione activity and acute phase protein, ceruloplasmin level in plasma did not revealed any major significant changes but indicated that oxidative stress was more in group II animals. Plasma cortisol level increased significantly (p < 0.01) after operation and testosterone level showed gradual decrease (p > 0.05) up to 7th postoperative day in animals of group II. On the basis of the parameters studied, it can be concluded that capnoperitoneum at 10 mm Hg pressure gradient and CO 2 at the flow rate of 2 liter/minute provides optimum visualization of intra-abdominal organs and found suitable for laparoscopic sterilization in male dogs. The laparoscopic vasectomy alone in male dogs was found comparatively quick, less time consuming and can be successfully applied for mass sterilization program. Oxidative stress in laparoscopic vasectomy (group I) was less as compared to other group.

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“…In group I, no significant change (p > 0.05) in testosterone was observed at different postoperative time intervals. It might be attributed to bilateral vasectomy which do not exert remarkable effect on steroidogenic functionality of the testicle as also reported by Batista et al 38 Whereas, in group II, a significant decrease (p < 0.01) in plasma testosterone was observed immediately after operation up to 7th postoperative day. It might be due to the reduction of testicular blood flow and loss of testicular interstitial tissue.…”

Section: Hormonal Estimationsupporting

confidence: 73%

Laparoscopic Vasectomy vs Laparoscopic Sterilization in Dogs: A Comparison of Two Techniques

Mahalingam¹,

Kumar²,

Maiti³

et al. 2014

WJOLS

View full text Add to dashboard Cite

Twelve clinically healthy, adult male dogs randomly equally divided into two groups (I and II). Animals of both the groups received xylazine-ketamine anesthesia. Laparoscopic bilateral vasectomy was performed in group I, whereas in animals of group II in additition to vasectomy, spermatic artery-vein plexus were clipped with titanium clips at a distance of 1 to 2 cm. Insufflation of abdominal cavity was achieved by CO 2 (2 liter/minute) at 10 mm Hg pressure gradient. Clinical observations revealed no significant changes. Differential leukocyte count (DLC) revealed significant neutrophilia and comparative lymphopenia on 3rd postoperative in both groups. Significant increase (p < 0.05) in plasma alkaline and acid phosphatase level was observed on day 3 postoperatively. Indices of oxidative stress viz lipid peroxidation (LPO), catalase (CAT), superoxide dismutase (SOD), reduced glutathione activity and acute phase protein, ceruloplasmin level in plasma did not revealed any major significant changes but indicated that oxidative stress was more in group II animals. Plasma cortisol level increased significantly (p < 0.01) after operation and testosterone level showed gradual decrease (p > 0.05) up to 7th postoperative day in animals of group II. On the basis of the parameters studied, it can be concluded that capnoperitoneum at 10 mm Hg pressure gradient and CO 2 at the flow rate of 2 liter/minute provides optimum visualization of intra-abdominal organs and found suitable for laparoscopic sterilization in male dogs. The laparoscopic vasectomy alone in male dogs was found comparatively quick, less time consuming and can be successfully applied for mass sterilization program. Oxidative stress in laparoscopic vasectomy (group I) was less as compared to other group.

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“…In other studies, it has been shown that bilateral vasectomy does not strongly affect the endocrine function of the testis over time [36] although it may result in damage to spermatogenesis in vasectomized rats [37]. …”

Section: Discussionmentioning

confidence: 99%

Prooxidant-antioxidant balance and malondialdehyde over time in adult rats after tubal sterilization and vasectomy

Faramarzi

¹

,

Seifi

²

,

Sadeghipour

³

et al. 2012

Clin Exp Reprod Med

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ObjectiveSterilization (tubal sterilization and vasectomy) is a widely applied contraceptive method worldwide. Although most studies have described sterilization as a safe method, there are reports of tubal ligation (TL) and vasectomy complications. The aim of this study was to evaluate the effects of TL and vasectomy on the serum oxidative stress, specifically prooxidant-antioxidant balance (PAB) and malondialdehyde (MDA) levels, over time.MethodsMale and female rats were classified into vasectomy, sham-vasectomy, TL, and sham-TL groups, respectively. The PAB and MDA levels were measured on days 15 and 45 and months 3 and 6 after the intervention. For female rats, blood sampling was performed during the diestrous phase and estradiol and progesterone were also measured.ResultsSerum PAB and MDA increased after TL (p<0.05). Vasectomy increased serum MDA remarkably after 45 days, 3 months, and 6 months (p<0.05). After vasectomy, serum PAB also increased although not significantly. Serum estradiol and progesterone decreased remarkably in the TL group compared to the sham group (p<0.05).ConclusionBilateral TL and vasectomy both increase the serum oxidative stress; however the imbalance after TL was very noticeable. As for the TL, the reduction of serum estrogen levels can be involved in this imbalance. Complications followed by TL or vasectomy could be due to increased levels of oxidants. Thus, prescribing antioxidants during and or after surgery may be a solution.

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Semen Characteristics and Plasma Levels of Testosterone after Bilateral Vasectomy in Bucks

Cited by 15 publications

References 12 publications

Laparoscopic Vasectomy vs Laparoscopic Sterilization in Dogs: A Comparison of Two Techniques

Laparoscopic Vasectomy vs Laparoscopic Sterilization in Dogs: A Comparison of Two Techniques

Laparoscopic Vasectomy vs Laparoscopic Sterilization in Dogs: A Comparison of Two Techniques

Prooxidant-antioxidant balance and malondialdehyde over time in adult rats after tubal sterilization and vasectomy

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